{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T20:06:12Z","timestamp":1770494772378,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Metastases to the pancreas are rare and can be confused with the primary adenocarcinoma of the pancreas. Metastasis of renal pelvis urothelial carcinomas to the pancreas are extremely rare. Endoscopic ultrasound\u2010guided fine\u2010needle aspiration (EUS\u2010FNA) biopsy is a very safe and effective diagnostic method. In this study, we present a 65\u2010year\u2010old male patient with a solitary mass in the pancreas. A moderate cellular tumoral lesion was observed in the aspiration cytology performed from the 55\u2010millimeter solid mass invading the head of the pancreas via EUS\u2010FNA. Tumor cells consisted of cells with irregular borders, different shapes and sizes, hyperchromatic, narrow cytoplasm with dark nuclei, and cells with anisonucleosis in focal areas. Cellblock obtained from aspirated was found diffusely positive with high molecular weight cytokeratin, Thrombomodulin, p63, GATA\u20103, and CK7, and negative with CK20, PAX8, and PSA. Having a primary malignancy in the medical history of the patients is very important in the differential diagnosis of primary and secondary pancreatic cancers. The potential for metastasectomy in pancreatic metastases can be applied in cases with isolated metastatic disease. Primary tumor histopathology may have an impact on the long\u2010term survival of the case. This study aimed to describe the cytomorphological features of solid and solitary pancreatic malignancies and to evaluate the role of immunohistochemistry performed from aspirate cell block in detecting the primary tumor origin.<\/jats:p>","DOI":"10.1002\/dc.24998","type":"journal-article","created":{"date-parts":[[2022,6,3]],"date-time":"2022-06-03T06:59:40Z","timestamp":1654239580000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An exceptionally rare case of metastatic high\u2010grade urothelial carcinoma of the renal pelvis to the pancreas diagnosed on endoscopic ultrasound\u2010guided fine\u2010needle aspiration: A diagnostic challenge"],"prefix":"10.1002","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0994-1275","authenticated-orcid":false,"given":"Ali","family":"Koyuncuer","sequence":"first","affiliation":[{"name":"Department of Pathology Umraniye Training and Research Hospital, University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00fcleyman","family":"Sayar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Health Sciences University, Umraniye Training and Research Hospital  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"It\u0131r Ebru","family":"Zemheri","sequence":"additional","affiliation":[{"name":"Department of Pathology Umraniye Training and Research Hospital, University of Health Sciences  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamil","family":"\u00d6zdil","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Health Sciences University, Umraniye Training and Research Hospital  \u0130stanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melike","family":"\u00d6z\u00e7elik","sequence":"additional","affiliation":[{"name":"Department of 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