{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:10:43Z","timestamp":1789665043179,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T00:00:00Z","timestamp":1659139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although the incidence of cervical cancer has decreased since the 1980s in Korea, it remains high among the elderly women. This study evaluated the suitability of cervical cancer screening for elderly Korean women aged \u226565\u2009years according to recommendations by the American Society of Cytopathology and American Society for Colposcopy and Cervical Pathology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed the records of patients who underwent cervical cancer screening, followed by liquid\u2010based Pap test, human papillomavirus (HPV) test, and colposcopic punch biopsy at two academic hospitals from May 2008 to May 2018. The participants were divided into two groups &lt;65 and \u226565\u2009years old. Logistic regression analysis was performed to evaluate the association between cytology tests, HPV tests and the occurrence of high\u2010risk lesions, \u2265cervical intraepithelial neoplasia2 (CIN2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean patient age was 49.02\u2009\u00b1\u200915.437 (range 15\u201391) years. No patients aged &lt;25\u2009years showed atypical squamous cell\u2010cannot exclude high grade (ASC\u2010H), squamous cell carcinoma (SCC), or adenocarcinoma (ADC). The incidence of high\u2010grade squamous intraepithelial lesion (HISL) (39.7%) and \u2265CIN 3 (40.2%) was significantly higher in patients \u226565\u2009years of age than in other age groups. However, patients \u226565\u2009years showed increased HSIL and HPV negativity and ASC\u2010H, HSIL, and HPV positivity in those with \u2265CIN 2 (both <jats:italic>p<\/jats:italic>\u00a0=\u00a0.043).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Korean women aged \u226565\u2009years should undergo cervical cancer screening. The relevance of HPV or Cytology test alone or co\u2010test for screening should be evaluated in this population.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.25021","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T20:53:11Z","timestamp":1659214391000},"page":"482-490","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The necessity of continuing cervical cancer screening of elderly Korean women aged 65\u2009years or older"],"prefix":"10.1002","volume":"50","author":[{"given":"Sumin","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Anam Hospital, Seongbuk Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2388-0111","authenticated-orcid":false,"given":"Seon\u2010Mi","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Anam Hospital, Seongbuk Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Anam Hospital, Seongbuk Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun\u2010Woong","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Guro Hospital, Guro Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Jin","family":"Min","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Ansan Hospital  Danwon Gu Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Hwa","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Guro Hospital, Guro Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae\u2010Yun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Anam Hospital, Seongbuk Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae\u2010Kwan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Guro Hospital, Guro Gu  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nak\u2010Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Korea University College of Medicine, Korea Ansan Hospital  Danwon Gu Gyeonggi\u2010do Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.21116"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2021.32.e12"},{"key":"e_1_2_10_4_1","unstructured":"Human Papillomavirus and Related Diseases Report. 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