{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:03:22Z","timestamp":1778331802258,"version":"3.51.4"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T00:00:00Z","timestamp":1673395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Extra neural metastasis of central nervous system oligodendroglioma is very rare. Oligodendroglioma is the seventh most frequently occurring neoplasm of central nervous system (CNS) with metastasis outside the CNS. According to literature, presence of metastasis in CNS was most frequently detected in patients of glioblastoma (41.4%), medulloblastoma (26.7%), ependymomas (16.4%), astrocytoma (10.3%) and oligodendroglioma (5.27%). A 38\u2010year\u2010old male patient presented with loss of vision and swelling on left side of neck since last 1\u2009week measuring 3\u2009x\u20092\u2009cm. He was operated for brain tumor 7\u2009years back, which was diagnosed as oligodendroglioma. Ultrasound sonography revealed multiple hypoechoic lymph nodes in bilateral cervical region largest measuring 4.5\u2009x\u20091.9\u00a0cm in left submandibular region. FNA of left submandibular lymph node was done, which revealed deposits of poorly differentiated malignancy. Cell block was prepared for carrying out ancillary studies which showed positivity for glial fibrillary acidic protein (GFAP), S\u2010100 and negativity for cytokeratin (CK), epithelial membrane antigen (EMA), LCA and progesterone receptor (PR). Based on previous history of oligodendroglioma, cytological and immunohistochemistry (IHC) findings a diagnosis of metastatic oligodendroglioma was made. Metastasis of oligodendroglioma to cervical lymph node should also be considered as one of the differential diagnoses. Diagnosing metastatic CNS tumor is extremely challenging for pathologists. It is essential to have the clinical information of a previous CNS tumor, including the histologic type and immunophenotype. Besides common malignancies of cervical lymph node, we should also think of CNS metastasis so that patient management will be early and proper.<\/jats:p>","DOI":"10.1002\/dc.25100","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T10:29:14Z","timestamp":1673432954000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Oligodendroglioma metastasizing to cervical lymph node: Rare entity diagnosed on fine\u2010needle aspiration cytology"],"prefix":"10.1002","volume":"51","author":[{"given":"Sant Prakash","family":"Kataria","sequence":"first","affiliation":[{"name":"Department of Pathology Pt. B. D. Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Mahak","sequence":"additional","affiliation":[{"name":"Department of Pathology Pt. B. D. Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pathology Pt. B. D. Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gajender","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Immunohematology and Blood transfusion Pt. B. D. Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunita","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology Pt. B. D. Sharma Post Graduate Institute of Medical Sciences  Rohtak Haryana India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S204346"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4065\/82.10.1271"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060\u2010006\u20109123\u20103"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1023\/b:neon.0000014519.61604.da"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1970.33.1.0088"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(79)80051-9"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198103000-00012"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-9-17"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2008.11.003"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/1793\u20105482.238010"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19851001)56:7 <1778::AID-CNCR2820561309>3.0.CO;2-I"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S348102"},{"key":"e_1_2_8_14_1","first-page":"40","article-title":"Cytology of primary neoplasms of the central nervous system","volume":"21","author":"Watson CW","year":"1977","journal-title":"Acta Cytol"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000325821"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.25100","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.25100","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.25100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T21:04:03Z","timestamp":1692392643000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.25100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,11]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/dc.25100"],"URL":"https:\/\/doi.org\/10.1002\/dc.25100","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,11]]},"assertion":[{"value":"2022-12-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}