{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:52:38Z","timestamp":1776693158118,"version":"3.51.2"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T00:00:00Z","timestamp":1675814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["2021R1G1A1091264"],"award-info":[{"award-number":["2021R1G1A1091264"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008005","name":"Yonsei University College of Medicine","doi-asserted-by":"publisher","award":["6\u20102021\u20100244"],"award-info":[{"award-number":["6\u20102021\u20100244"]}],"id":[{"id":"10.13039\/501100008005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although several studies have documented the histological features of uterine mesonephric\u2010like adenocarcinoma (MLA), its cytological features have been rarely reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We searched for histologically confirmed uterine MLA cases in the pathology archives of three institutions between 2010 and 2021. All available cytology slides were examined to identify the cytological features of uterine MLA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 16 patients with uterine MLA and reviewed the slides obtained from 21 cytology samples. Samples were obtained from the cervicovagina (9\/21, 42.9%), peritoneal washing (8\/21, 38.1%), pleural effusion (2\/21, 9.5%), and transbronchial needle aspiration of mediastinal lymph node (2\/21, 9.5%). Preparation methods included ThinPrep (11\/21, 52.4%), SurePath (8\/21, 38.1%), and conventional smear (2\/21, 9.5%). Regardless of the sampling site and preparation method, cytology samples displayed tight three\u2010dimensional cellular clusters showing monotonous, small\u2010to\u2010medium\u2010sized, round, hyperchromatic nuclei, indistinct nucleoli, scant cytoplasm, and high nuclear\u2010to\u2010cytoplasmic ratio. Approximately half of the samples (10\/21, 47.6%) showed hyaline\u2010like globules. Mitotic figures (7\/21, 33.3%) and apoptotic bodies (13\/21, 61.9%) were also observed. No tumor diathesis or nuclear feathering was identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Irrespective of sampling site and preparation method, the majority of uterine MLA cases showed the following cytological features: tight three\u2010dimensional cellular clusters showing small\u2010to\u2010medium\u2010sized, round, hyperchromatic nuclei with indistinct nucleoli and high nuclear\u2010to\u2010cytoplasm ratio. In case a cytology sample suspicious of a glandular lesion displays these cytological features, which are distinct from those of endocervical adenocarcinoma, uterine MLA should be included in the differential diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.25111","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T07:18:07Z","timestamp":1675927087000},"page":"294-306","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cytological features of mesonephric\u2010like adenocarcinoma of the uterine corpus"],"prefix":"10.1002","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4595-3836","authenticated-orcid":false,"given":"Youjeong","family":"Seo","sequence":"first","affiliation":[{"name":"Department of Pathology Inha University Hospital  Incheon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2658-5054","authenticated-orcid":false,"given":"Eunhyang","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pathology, Severance Hospital Yonsei University College of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2356-7822","authenticated-orcid":false,"given":"Hyun\u2010Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Pathology and Translational Genomics, Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000471"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2015.103"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12895"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000958"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001401"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001612"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001873"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000991"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.21873\/cgp.20338"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.3886"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-021-00799-6"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11112042"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001142"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31824a72c6"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-019-03123-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10040698"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11040717"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.15272"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000764"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2012.00959.x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22160"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24675"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-200304000-00002"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2005.00265.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200103000-00013"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-11074-5"}],"container-title":["Diagnostic 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