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Extragonadal germ cell tumors are characterized by their midline locations including pineal and suprasellar regions, mediastinum, retroperitoneum and sacrococcyx. These tumors have also been reported in rare locations such as prostate, bladder, vagina, liver and scalp. Extragonadal germ cell tumors can be primary but may also represent metastases from primary gonadal germ cell tumors. In this report we describe a case of a duodenal seminoma in a 66\u2010year\u2010old male with no history of testicular tumors, who presented with upper gastrointestinal bleed as the initial manifestation. He was effectively treated with chemotherapy and continues to progress well clinically, with no episodes of recurrence.<\/jats:p>","DOI":"10.1002\/dc.25119","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T08:02:11Z","timestamp":1677744131000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Upper gastrointestinal bleed as the initial presentation of seminoma involving the duodenum in an elderly patient with 9\u00a0year follow up: A case report and literature review"],"prefix":"10.1002","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3158-1261","authenticated-orcid":false,"given":"Liena","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Western Ontario  London Ontario 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