{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T01:24:45Z","timestamp":1766712285154,"version":"3.40.5"},"reference-count":53,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Endoscopic ultrasound\u2013guided fine\u2010needle aspiration biopsy (EUS\u2013FNAB) is useful for preoperatively diagnosing various pancreatic tumors. Although there is a risk of complications, such as pancreatitis, this procedure achieves the crucial need of reducing unnecessary invasive surgery for benign lesions. Herein, we reported a surgically resected case of pancreatic hamartoma in the pancreatic head whose retrospective analysis revealed that the specimens obtained via EUS\u2013FNAB contained hamartoma fragments. Pancreatic hamartoma is an extremely rare benign disease that is exceptionally difficult to diagnose before surgical resection owing to its rarity and lack of established imaging findings. To the best of our knowledge, the preoperative diagnosis of pancreatic hamartoma via EUS\u2013FNAB specimens has not been reported to date. Herein, postoperative EUS\u2013FNAB evaluation revealed a collection of pancreatic hamartoma lesions, although the initial diagnosis was pancreatic tissue with focal atrophy and fibrosis. Diagnosis using EUS\u2013FNAB can be challenging owing to the very small sample size. If mature acini and ducts with fibrous stroma without islets are observed in the EUS\u2013FNAB specimen, pancreatic hamartoma should be considered as a differential diagnosis. Thus, careful follow\u2010up or reexamination of EUS\u2013FNAB should be considered instead of surgery if a benign lesion is suspected preoperatively.<\/jats:p>","DOI":"10.1002\/dc.25174","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T11:09:44Z","timestamp":1685531384000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pancreatic hamartoma: Possibility of a preoperative diagnosis via endoscopic ultrasound\u2013guided fine\u2010needle aspiration biopsy"],"prefix":"10.1002","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3101-9212","authenticated-orcid":false,"given":"Hiroshi","family":"Shintaku","sequence":"first","affiliation":[{"name":"Department of Pathology Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Gokita","sequence":"additional","affiliation":[{"name":"Department of 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