{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:52:03Z","timestamp":1747147923962,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cell blocks (CB) are an established technique in non\u2010gynecological cytology, but experience in gynecological cytology is still relatively limited. In this study, we compared the diagnostic agreement between liquid\u2010based cytology (LBC) and CB using whole slide digital imaging (WSI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>WSI of 82 specimens (41 LBC and 41 CB) were evaluated independently by three observers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The overall agreement was 0.463 for all 82 cases including both LBC and CB, 0.439 for LBC alone, and 0.484 for CB alone. Agreement was highest for HSIL, NILM, cancers and lower for borderline (ASC\u2010US, ASC\u2010H). There was no significant difference in agreement between LBC and CB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>WSI of CB can be used for the diagnosis of cervical lesions and may be particularly useful in cases with high atypical cellularity or large hyperchromatic cell groups.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.25411","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T08:13:58Z","timestamp":1728634438000},"page":"43-47","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Agreement in Whole Slide Digital Images of\u00a0Cervical Cytology and Cell Blocks"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9194-8782","authenticated-orcid":false,"given":"Giovanni","family":"Negri","sequence":"first","affiliation":[{"name":"Pathology Unit Central Hospital Bolzano, Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversit\u00e4t  Bolzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Tauber","sequence":"additional","affiliation":[{"name":"Pathology Unit Central Hospital Bolzano, Lehrkrankenhaus der Paracelsus Medizinischen Privatuniversit\u00e4t  Bolzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Pinamonti","sequence":"additional","affiliation":[{"name":"Department of Pathology Azienda Sanitaria Universitaria Integrata Di Trieste  Trieste Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Golinelli","sequence":"additional","affiliation":[{"name":"College of Health Care\u2010Professions Claudiana  Bozen Italy"},{"name":"Laboratorio di Biochimica Clinica Central Hospital Bolzano  Bolzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maja","family":"Garofalo","sequence":"additional","affiliation":[{"name":"College of Health Care\u2010Professions Claudiana  Bozen Italy"},{"name":"Laboratorio di Biochimica Clinica Central Hospital Bolzano  Bolzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabio","family":"Vittadello","sequence":"additional","affiliation":[{"name":"Explora\u2010Research and Statistical Analysis  Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arrigo","family":"Capitanio","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology Link\u00f6ping University Hospital  Link\u00f6ping Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,11]]},"reference":[{"volume-title":"Female Genital Tumors. 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