{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T04:06:41Z","timestamp":1746158801858,"version":"3.40.4"},"reference-count":11,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T00:00:00Z","timestamp":1742947200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Port\u2010site metastasis (PSM) following laparoscopic cholecystectomy (LC) for unsuspected gallbladder carcinoma (GBC) is a rare occurrence. Fine Needle Aspiration Cytology is a simple and time\u2010saving technique, thus it has proven useful in diagnosing such metastases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>We present a case of a 45\u2010year\u2010old female who developed painful, multinodular epigastric swellings 2\u2009years post\u2010LC, initially performed for presumed benign cholelithiasis. FNAC of the port\u2010site swelling revealed hypercellular smears with malignant epithelial cells, leading to a diagnosis of poorly differentiated malignancy. Follow\u2010up imaging and histopathology confirmed incidental primary gallbladder carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Port site metastasis in gallbladder carcinoma has a poor prognosis; thus, early detection and intervention are essential. Advanced imaging and FNAC under guidance serve as critical tools for early diagnosis, especially in cases lacking prior histological examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case highlights the critical role of vigilant post\u2010surgical monitoring and comprehensive histopathological analysis following cholecystectomy, especially in areas with a higher incidence of gallbladder carcinoma. FNAC also plays a valuable diagnostic modality for early detection and management of Port site metastasis in unsuspected gallbladder carcinoma cases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.25469","type":"journal-article","created":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T07:32:05Z","timestamp":1742974325000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>FNAC<\/scp> Diagnosis of Rare Port\u2010Site Metastasis in Gallbladder Cancer Post\u2010Cholecystectomy"],"prefix":"10.1002","volume":"53","author":[{"given":"Arushi","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Pathology HIMSR, Jamia Hamdard  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3400-9527","authenticated-orcid":false,"given":"Durre","family":"Aden","sequence":"additional","affiliation":[{"name":"Department of Pathology HIMSR, Jamia Hamdard  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabina","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Pathology HIMSR, Jamia Hamdard  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nehal","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Pathology HIMSR, Jamia Hamdard  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/967472"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.08.007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12296"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/1742-6413.113627"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i22.5729"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.21474\/IJAR01\/18968"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/cytojournal.cytojournal_5_18"},{"issue":"2","key":"e_1_2_8_9_1","first-page":"173","article-title":"Immunohistochemical Expression of Ki\u201067 in Gall Bladder Carcinoma","volume":"5","author":"Ojha A.","year":"2018","journal-title":"Indian Journal of Pathology and Oncology"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.18203\/2349-2902.isj20150949"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2298\/aci1201105r"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00210930"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.25469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T10:47:00Z","timestamp":1746096420000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.25469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,26]]},"references-count":11,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1002\/dc.25469"],"URL":"https:\/\/doi.org\/10.1002\/dc.25469","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2025,3,26]]},"assertion":[{"value":"2025-02-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}