{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T01:01:31Z","timestamp":1775696491189,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T00:00:00Z","timestamp":1747612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Fine needle aspiration cytology (FNAC) is a cost\u2010effective method used for preoperative diagnosis of salivary gland lesions. Due to the wide range of tumor types, overlapping morphology, and limited cellularity, diagnosing salivary gland lesions on FNAC can be challenging. A pattern\u2010based approach focusing on cellular and architectural features possible on core needle biopsy (CNB) can help refine differential diagnoses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to assess the concordance between FNAC and histological diagnoses obtained from CNB, as well as examine the risk of malignancy (ROM), and evaluate the agreement between histopathological assessments and diagnoses of these lesions in both CNB and resection specimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A retrospective observational study was conducted in the Department of Oncopathology at a tertiary cancer center of North India over a period of 5\u2009years. Cases wherein diagnosis offered on two modalities\u2014FNAC and CNB were\u2014available, were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 105 cases were identified. Category VI was the predominant category (60.95%) and the ROM in categories II, III, and IV was higher compared to that mentioned in the Milan System for Reporting Salivary Gland Cytopathology. Correlation between FNAC and CNB was achieved in 78.1% of cases, and between CNB and the final diagnosis on resection specimen was attained in 100% of cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The limitations of FNAC can be obviated by the utilization of CNB. Ancillary studies such as immunohistochemistry and\/or cytogenetics wherever necessary can be smoothly applied on biopsy material, establishing the precise diagnosis and thereby providing definitive direction to further management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/dc.25487","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T07:50:00Z","timestamp":1747641000000},"page":"391-401","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Myriad Spectrum of Salivary Gland Lesions: Cytohistological Correlation on Fine Needle Aspiration Cytology, Core Needle Biopsy, and Resections in a 5\u2010Year Single Institutional Experience of North India"],"prefix":"10.1002","volume":"53","author":[{"given":"Zachariah","family":"Chowdhury","sequence":"first","affiliation":[{"name":"Department of Oncopathology, Mahamana Pandit Madan Mohan Malviya Cancer Centre &amp; Homi Bhabha Cancer Hospital [Tata Memorial Centre] (Units of Tata Memorial Centre Under Department of Atomic Energy, Government of India) Homi Bhabha National Institute  Varanasi Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9388-1596","authenticated-orcid":false,"given":"Pallavi","family":"Majumdar","sequence":"additional","affiliation":[{"name":"Department of Oncopathology, Mahamana Pandit Madan Mohan Malviya Cancer Centre &amp; Homi Bhabha Cancer Hospital [Tata Memorial Centre] (Units of Tata Memorial Centre Under Department of Atomic Energy, Government of India) Homi Bhabha National Institute  Varanasi Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumeet","family":"Narain","sequence":"additional","affiliation":[{"name":"Department of Oncopathology, Mahamana Pandit Madan Mohan Malviya Cancer Centre &amp; Homi Bhabha Cancer Hospital [Tata Memorial Centre] (Units of Tata Memorial Centre Under Department of Atomic Energy, Government of India) Homi Bhabha National Institute  Varanasi Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Komal","family":"Lamba","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Oncosurgery, Mahamana Pandit Madan Mohan Malviya Cancer Centre &amp; Homi Bhabha Cancer Hospital [Tata Memorial Centre] (Units of Tata Memorial Centre Under Department of Atomic Energy, Government of India) Homi Bhabha National Institute  Varanasi Uttar Pradesh India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2023.04.010"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105\u2010022\u201001420\u20101"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320927912"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11121912"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.4132\/jptm.2020.06.09"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/jmp2020012"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP5LTQ4RVOQAIT"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21821"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2011.12.005"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.20873"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24109"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100145785"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010017\u20105295\u20109"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2015.03.015"},{"issue":"9","key":"e_1_2_13_16_1","first-page":"1608","article-title":"Ultrasonography\u2010Guided Core\u2010Needle Biopsy of Parotid Gland Masses","volume":"25","author":"Wan Y. 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