{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:22:50Z","timestamp":1755217370191,"version":"3.43.0"},"reference-count":10,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms typically arising in the stomach and small intestine and rarely involving extra\u2010gastrointestinal organs. While fine\u2010needle aspiration (FNA) offers reliable diagnosis, exfoliation of GIST cells into body fluids is exceedingly rare and diagnostically challenging. We report a case of a 69\u2010year\u2010old male with metastatic GIST in ascitic fluid. The cells revealed atypical epithelioid morphology with high nuclear\u2010to\u2010cytoplasmic ratio and nuclear irregularities. Immunohistochemistry (IHC) demonstrated positivity for CD117 and DOG1. Diagnosis requires integration of clinical history, cytomorphology, and a broad IHC panel. Awareness of its cytologic features, application of mesenchymal markers, and molecular testing are critical for accurate diagnosis and effective clinical management.<\/jats:p>","DOI":"10.1002\/dc.25499","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T01:54:11Z","timestamp":1750816451000},"page":"462-465","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cytological Assessment of Metastatic Gastrointestinal Stromal Tumor in Ascitic Fluid"],"prefix":"10.1002","volume":"53","author":[{"given":"Hadi","family":"Sultan","sequence":"first","affiliation":[{"name":"Charles E. Schmidt College of Medicine Florida Atlantic University  Boca Raton Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4671-2148","authenticated-orcid":false,"given":"Zohre","family":"Sadeghian","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Pathology and Laboratory Medicine Institute  Weston Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elvia","family":"Goez\u2010Gutierrez","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Pathology and Laboratory Medicine Institute  Weston Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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