{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T05:40:05Z","timestamp":1756791605144,"version":"3.44.0"},"reference-count":8,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Acinic cell carcinoma (ACC) is a rare malignant tumor of the head and neck region. It accounts for 12.4%\u201317.4% of parotid gland malignancies and approximately 3.4% of all salivary gland tumors. ACC is a low\u2010grade salivary gland malignancy that predominantly affects females. In some cases, ACC can undergo high\u2010grade transformation (HGT), resulting in more aggressive behavior. Here, we present a rare case of recurrent Acinic cell carcinoma with aggressive features and high\u2010grade cytomorphology\u2014including increased cellularity, papillary and singly scattered cells, high nuclear\u2010to\u2010cytoplasmic (N:C) ratio, coarse chromatin, and single\u2010cell necrosis in the background\u2014diagnosed via fine\u2010needle aspiration cytology (FNAC) and further confirmed by histopathology and immunohistochemistry. This case can be categorized as ACC recurrence associated with high\u2010grade transformation (HGT).<\/jats:p>","DOI":"10.1002\/dc.25505","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T03:49:50Z","timestamp":1752724190000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent Acinic Cell Carcinoma of Parotid Gland Diagnosed by Fine Needle Aspiration Cytology: A Rare Case Report"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8514-422X","authenticated-orcid":false,"given":"Anju","family":"Khairwa","sequence":"first","affiliation":[{"name":"Department of Pathology University College of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priya","family":"Suneja","sequence":"additional","affiliation":[{"name":"Department of Pathology University College of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9915-8227","authenticated-orcid":false,"given":"Preeti","family":"Diwaker","sequence":"additional","affiliation":[{"name":"Department of Pathology University College of Medical Sciences  New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2014.10.007"},{"key":"e_1_2_7_3_1","first-page":"103","article-title":"Cytological Characteristics of Acinic Cell Carcinoma (ACC) Diagnosed by Fine\u2010Needle Aspiration Biopsy (FNAB).A Study of Four Cases","volume":"10","author":"Prieto\u2010Rodr\u00edguez M.","year":"2005","journal-title":"Medicina Oral, Patolog\u00eda Oral y Cirug\u00eda Bucal"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016481003796801"},{"issue":"4","key":"e_1_2_7_5_1","first-page":"235","article-title":"Fine Needle Aspiration of Salivary Gland Carcinomas With High\u2010Grade Transformation: A Multi\u2010Institutional Study of 22 Cases and Review of the Literature","volume":"129","author":"Nakaguro M.","year":"2020","journal-title":"Cancer Cytopathology"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2014.03.017"},{"volume-title":"Diagnostic Histopathology of Tumours","year":"2022","author":"Fletcher's C. D. M.","key":"e_1_2_7_7_1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22496"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.57"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.25505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T05:00:20Z","timestamp":1756789220000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.25505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,16]]},"references-count":8,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/dc.25505"],"URL":"https:\/\/doi.org\/10.1002\/dc.25505","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2025,7,16]]},"assertion":[{"value":"2025-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}