{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T15:22:33Z","timestamp":1697988153262},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":7073,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1987,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Two\u2010hundred and fifty discrete lesions of the lung and mediastinum were sampled by a modified fine\u2010needle aspiration biopsy (FNAB) technique. Aspirates were collected directly into 15 ml of Saccomanno's fixative, and all preparative work was carried out in the cytopathology laboratory. Only seven aspirates were \u201cinsufficient for diagnosis,\u201d giving a productivity rate of 97%. Five insufficient aspirates later proved to be neoplasms. Of the 243 cases with a primary FNAB diagnosis, 21 had insignificant disease, 29 had benign neoplasms or nonneoplastic disease, and 193 had malignant tumors. Most malignancies could be assigned to a specific histologic type by FNAB; those that proved difficult by FNAB were usually difficult on histopathologic examination. There were no false\u2010positive diagnoses of malignancy and only eight false\u2010negative results. Of 12 results interpreted as \u201cSuspicious,\u201d 10 proved to be malignant on follow\u2010up. This modified method has proven to have a low complication rate and to be both highly productive and reliable in the diagnosis of malignant and nonmalignant disease. Diagn Cytopathol 1987;3:1\u20137.<\/jats:p>","DOI":"10.1002\/dc.2840030102","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T01:43:14Z","timestamp":1172108594000},"page":"1-7","source":"Crossref","is-referenced-by-count":8,"title":["The reliability of fine\u2010needle aspiration biopsy in the diagnosis of deep lesions of the lung and mediastinum: Experience with 250 cases using a modified technique"],"prefix":"10.1002","volume":"3","author":[{"given":"Geraldine P.","family":"Young","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irving","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel F.","family":"Cowan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca L.","family":"Blei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"172","article-title":"Transthoracic fine\u2010needle aspiration cytology; a study of 301 aspirations from 221 cases","volume":"26","author":"Malberger E","year":"1982","journal-title":"Acta Cytol"},{"key":"e_1_2_1_3_2","first-page":"177","volume-title":"Handbook of fine needle aspiration biopsy cytology","author":"Kline TS","year":"1981"},{"key":"e_1_2_1_4_2","first-page":"7","volume-title":"Clinical aspiration cytology","author":"Linsk JA","year":"1983"},{"key":"e_1_2_1_5_2","first-page":"45","article-title":"Carbowax fixation of needle aspiration biopsies","volume":"25","author":"West WF","year":"1981","journal-title":"Acta Cytol"},{"key":"e_1_2_1_6_2","first-page":"5","article-title":"Tissue fragments in fine needle aspirates as minibiopsies. 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