{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:55:42Z","timestamp":1784174142441,"version":"3.55.0"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":7073,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1987,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A retrospective analysis of 5,255 pleural effusion specimens from 3,811 patients was undertaken to determine the accuracy of cytopathologic correlation with pleural biopsy, the detection rate of malignancy by cytology, and the frequency distribution of malignant effusions according to age group. The cytopathologic correlation was 96.5% accurate, with 0.1% false\u2010positive results and 0.18% false\u2010negative results by cytology. The sensitivity of cytologic detections was 6.7% higher than that of pleural biopsy. Frequency analysis showed that the incidence of carcinoma of the lung, the most common cause of malignant effusion, is not sex based. Adenocarcinoma of the lung was the most frequent type of malignancy found in pleural effusions. It represented 79% of lung carcinomas that metastasized to pleura, accounting for 40% of all malignant pleural effusions. In young adults, lymphoreticular malignancies were the most common cause of malignant effusions. Diagn Cytopathol 1987;3:8\u201312.<\/jats:p>","DOI":"10.1002\/dc.2840030103","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T01:43:14Z","timestamp":1172108594000},"page":"8-12","source":"Crossref","is-referenced-by-count":118,"title":["Cytologic detection of malignancy in pleural effusion: A review of 5,255 samples from 3,811 patients"],"prefix":"10.1002","volume":"3","author":[{"given":"Chih","family":"Hsu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"22","volume-title":"International Histological Classification of Tumours","author":"Kreyberg L","year":"1981"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850815)56:4<905::AID-CNCR2820560435>3.0.CO;2-U"},{"key":"e_1_2_1_4_2","unstructured":"Hong Kong Government.Annual report: Chest service of the Government Medical and Health Department Hong Kong Part 2 Appendices 4 12 1980."},{"key":"e_1_2_1_5_2","first-page":"911","volume-title":"Diagnostic Cytology and Its Histopathologic Bases","author":"Koss LG","year":"1979"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830715)52:2<369::AID-CNCR2820520231>3.0.CO;2-7"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/72.1.48"},{"key":"e_1_2_1_8_2","first-page":"455","article-title":"A critical evaluation of 3,000 cytologic analyses of pleural fluid, ascitic fluid and pericardial fluid","volume":"10","author":"Lopes Cardozo P","year":"1966","journal-title":"Acta Cytol"},{"key":"e_1_2_1_9_2","first-page":"508","article-title":"A comparative study of the accuracy of cancer cell detection by cytological methods","volume":"6","author":"Von Haam E","year":"1962","journal-title":"Acta Cytol"},{"key":"e_1_2_1_10_2","first-page":"427","article-title":"Pleuritis by radiation, report of two cases","volume":"25","author":"Fentanes de Torres E","year":"1981","journal-title":"Acta Cytol"},{"key":"e_1_2_1_11_2","first-page":"373","article-title":"Blind pleural biopsy in combination with cytology of pleural effusions","volume":"25","author":"Winkelmann M","year":"1981","journal-title":"Acta Cytol"},{"key":"e_1_2_1_12_2","first-page":"412","article-title":"Malignant\u2010appearing cells in pleural effusion due to pancreatitis: Case report and literature review","volume":"25","author":"Kutty CPK","year":"1981","journal-title":"Acta Cytol"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840030103","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840030103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T07:59:26Z","timestamp":1697875166000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840030103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,3]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1987,3]]}},"alternative-id":["10.1002\/dc.2840030103"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840030103","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,3]]}}}