{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:27:40Z","timestamp":1788920860975,"version":"build-2803163510"},"reference-count":8,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":6889,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1987,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A short\u2010term estrogen test was used to obtain a correct cytologic diagnosis in 73 patients with an equivocal atrophic cellular pattern. Overestimation in cytodiagnosis was markedly eliminated, and the correct cytologic diagnosis was made in 81 % of the cell samples after the estrogen test. The purpose of this study was not only to confirm the usefulness of the short\u2010term estrogen test, but also to observe the cytomorphologic changes before and after the test. Thick cytoplasm, vacuoles in the cytoplasm, and a distinct cell border increased, while the amorphous chromatin pattern was eliminated after the estrogen test. Maturation of atypical cells in cases of dysplasia, carcinoma in situ, and invasive squamous\u2010cell carcinoma was investigated before and after the estrogen test. Although malignant cells were not influenced by estrogen, maturation of dysplastic cells was induced after the test.<\/jats:p>","DOI":"10.1002\/dc.2840030302","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T01:41:07Z","timestamp":1172108467000},"page":"181-184","source":"Crossref","is-referenced-by-count":8,"title":["Short\u2010term estrogen test for cytodiagnosis in postmenopausal women"],"prefix":"10.1002","volume":"3","author":[{"given":"Masamichi","family":"Kashimura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Baba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuji","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keita","family":"Matsukuma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiharu","family":"Kamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(49)90439-1"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.5795\/jjscc.22.703"},{"key":"e_1_2_1_4_2","first-page":"482","article-title":"The estrogen test: an aid in differential cytodiagnosis","volume":"18","author":"Keebler CM","year":"1974","journal-title":"Acta Cytol"},{"key":"e_1_2_1_5_2","volume-title":"Diagnosis of uterine cervix by the vaginal smear","author":"Papanicolaou GN","year":"1943"},{"key":"e_1_2_1_6_2","first-page":"103","volume-title":"Monographs in clinical cytology","author":"Patten SF","year":"1978"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(56)90576-2"},{"key":"e_1_2_1_8_2","first-page":"184","volume-title":"Diagnostic cytology and its histopathologic bases","author":"Koss LG","year":"1979"},{"key":"e_1_2_1_9_2","first-page":"410","article-title":"Does the induced proliferation of the initially atrophic epithelium persist longer than the possible duration of the actual effect of the administered estrogen?","volume":"2","author":"Wied GL","year":"1958","journal-title":"Acta Cytol"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840030302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840030302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T02:39:43Z","timestamp":1697855983000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840030302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,9]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1987,9]]}},"alternative-id":["10.1002\/dc.2840030302"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840030302","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,9]]}}}