{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:38:44Z","timestamp":1760981924291},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":6220,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1989,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Apocrine metaplastic cells are frequently present in fine\u2010needle aspirates (FNAs) of breast lesions, especially fibrocystic disease. Occasionally, apocrine cells may be atypical and present diagnostic difficulties. The morphologic features of six breast FNAs that contained atypical apocrine cells were analyzed and compared with benign apocrine cells in breast aspirates. In the six abnormal cases, the large, pleomorphic, atypical apocrine cells were the predominant cell type and occurred singly and in syncytial tissue fragments. The cells had large, eccentric, vesicular nuclei and usually multiple macronucleoli. The histologic diagnoses in the cases were apocrine carcinoma (five cases) and atypical apocrine metaplasia (one case). In comparison, benign apocrine cells are relatively small and uniform and arranged in cohesive, orderly sheets. It is concluded that, in breast FNAs. the predominance of atypical apocrine cells, occurring singly and in syncytia, should raise the suspicion of carcinoma.<\/jats:p>","DOI":"10.1002\/dc.2840050304","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T01:50:45Z","timestamp":1172109045000},"page":"248-254","source":"Crossref","is-referenced-by-count":9,"title":["The significance of atypical apocrine cells in fine\u2010needle aspirates of the breast"],"prefix":"10.1002","volume":"5","author":[{"given":"Terri L.","family":"Johnson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudha R.","family":"Kini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"Diseases of the breast","author":"Haagensen CD","year":"1986"},{"key":"e_1_2_1_3_2","volume-title":"Breast diseases","author":"Harris JR","year":"1987"},{"key":"e_1_2_1_4_2","first-page":"105","article-title":"Immunohistochemistry of a gross cystic disease fluid protein (GCDFP\u201015) of the breast. 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A morphologic and immunocytochemical study","volume":"123","author":"Eusebi V","year":"1986","journal-title":"Am J Pathol"},{"key":"e_1_2_1_21_2","volume-title":"Problems in breast pathology","author":"Azzopardi JG","year":"1979"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(84)80053-2"},{"key":"e_1_2_1_23_2","first-page":"322","article-title":"Mixed apocrine\u2010medullary carcinoma of the breast. Report of a case with fine needle aspiration cytology","volume":"31","author":"Burt AD","year":"1987","journal-title":"Acta Cytol"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01807652"},{"key":"e_1_2_1_25_2","doi-asserted-by":"crossref","unstructured":"BryantJ. 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