{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:54:52Z","timestamp":1788908092427,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":5977,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1990,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The fine\u2010needle aspiration (FNA) cytology of two cases of granulocytic sarcoma involving the breast is reported along with the FNA cytology of one case of myeloid metaplasia (extramedullary hematopoiesis) involving an axillalry lymph node. Two patients had known myeloproliferative disorders, while granulocytic sarcoma of the breast was the initial presentation of an unsuspected acute granulocytic leukemia in the other patient. Diff\u2010Quik\u2010stained preparations aided in the diagnosis of all three cases. Immunoperoxidase stains for factor VIII\u2010related antigen helped confirm the megakaryocytic differentiation of the cells in the FNA cytology of myeloid metaplasia. Electron microscopic (EM) examination performed on the aspirated material also showed megakaryocytic differentiation of the bizarre cells. FNA cytology can make a specific diagnosis of granulocytic sarcoma and myeloid metaplasia. The workup of these unusual extramedullary myeloproliferative masses was aided when immunocytochemistry and EM were performed on the aspirated material.<\/jats:p>","DOI":"10.1002\/dc.2840060207","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T01:49:01Z","timestamp":1172108941000},"page":"106-111","source":"Crossref","is-referenced-by-count":21,"title":["Fine\u2010needle aspiration cytology of granulocytic sarcoma and myeloid metaplasia"],"prefix":"10.1002","volume":"6","author":[{"given":"Jan F.","family":"Silverman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim R.","family":"Geisinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kim Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Strausbauch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Frable","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"67","article-title":"Fine needle aspiration biopsy of a granulocytic sarcoma (chloroma) of the breast","volume":"32","author":"Pettinato G","year":"1988","journal-title":"Acta Cytol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197909)44:3<1017::AID-CNCR2820440333>3.0.CO;2-I"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197604)37:4<1808::AID-CNCR2820370427>3.0.CO;2-U"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1182\/blood.V56.1.104.104","article-title":"Chloroma (granulocytic sarcoma) without evidence of leukemia: facilitated light microscopic diagnosis","volume":"56","author":"Mc Carty KS","year":"1980","journal-title":"Blood"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810915)48:6<1426::AID-CNCR2820480626>3.0.CO;2-G"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840020411"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/84.1.125"},{"key":"e_1_2_1_9_2","first-page":"233","volume-title":"Aspiration biopsy cytology: part 2: cytology of infradiaphragmatic organs","author":"Soderstrom N.","year":"1979"},{"key":"e_1_2_1_10_2","first-page":"176","volume-title":"Manual and atlas of fine needle aspiration cytology","author":"Orell SR","year":"1986"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(85)90034-0"},{"key":"e_1_2_1_12_2","first-page":"291","article-title":"Fine\u2010needle aspiration cytology of neoplasms metastatic to the breast","volume":"31","author":"Silverman JF","year":"1987","journal-title":"Acta Cytol"},{"key":"e_1_2_1_13_2","volume-title":"Thin needle aspiration biopsy","author":"Frable WJ","year":"1983"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.223.13.1488"},{"key":"e_1_2_1_15_2","first-page":"C8\u2010411","article-title":"Cytologic patterns in fine needle aspirations of nonepithelial lesions of lymph nodes","volume":"12","author":"Salazar GH","year":"1984","journal-title":"Cytopathol Check Sample"},{"key":"e_1_2_1_16_2","first-page":"63","article-title":"Granulocytic sarcoma with pleural involvement: identification of neoplastic cells with cytochemistry","volume":"29","author":"Yam LT","year":"1985","journal-title":"Acta Cytol"},{"key":"e_1_2_1_17_2","unstructured":"NewlandJR. 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