{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T16:42:38Z","timestamp":1714754558884},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":5612,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Nine malignant pleural effusions due to lymphoma were immunocytochemically analyzed with the peroxidase\u2010antiperoxidase adhesive slide assay for detection of cell surface antigens using a broad panel of monoclonal antibodies. The study population included one case of hairy\u2010cell leukemia; four cases of B cell non\u2010Hodgkin's lymphoma (B\u2010NHL), low malignant grade; two cases of B\u2010NHL, high malignant grade; one case of Hodgkin's disease; and one case of plasmacytoma. In the cases of B cell lymphoma, high percentages of B cells with monoclonal staining for kappa were found. In hairy\u2010cell leukemia, the hairy cells reacted with the monoclonal antibodies CD20, CD25, HLA\u2010DR, CD45, and HLA\u20101. In Hodgkin's disease, the Hodgkin cells reacted with CD15, CD20, CD25, CD30, T\u00fc9, and OKT9. The plasmacytoma case showed tumor cells negative for CD20, HLA\u2010DR, and CD45; partially positive for CD38; positive for HLA\u20101; rnonoclonally positive for lambda; and negative for heavy\u2010chain immunoglobulins. The analysis of nonmalignant lymphocyte subpopulations revealed CD4\/CD8 ratios similar to those in effusions of other etiologies. The percentages of natural killer cells (Leu\u20107\u2010positive and CD16\u2010positive) were small and also similar to percentages in effusions of other etiologies. We conclude that immunocytochemical analysis of pleural effusions allows a clear recognition of B lymphoma cells and also of Hodgkin and hairy cells and that the distribution of nonmalignant lymphocyte subsets is indistinguishable from those found in other malignant and nonmalignant effusions.<\/jats:p>","DOI":"10.1002\/dc.2840070202","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T01:44:18Z","timestamp":1172108658000},"page":"113-118","source":"Crossref","is-referenced-by-count":11,"title":["Malignant lymphoma in pleural effusions: An immunocytochemical cell surface analysis"],"prefix":"10.1002","volume":"7","author":[{"given":"Josune","family":"Guzman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus J.","family":"Bross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Costabel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.34.12.1311"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/82.6.666"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.38.6.608"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.35.11.1216"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00708329"},{"key":"e_1_2_1_7_2","first-page":"833","article-title":"Immunocytochemical diagnosis of lymphoma in serous effusions","volume":"29","author":"Yam LT","year":"1985","journal-title":"Acta Cytol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.3.590"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840050206"},{"key":"e_1_2_1_10_2","first-page":"187","article-title":"The value of the immunoperoxidase slide assay in the diagnosis of malignant pleural effusions in breast cancer","volume":"32","author":"Guzman J","year":"1988","journal-title":"Acta Cytol"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197806000-00011"},{"key":"e_1_2_1_12_2","first-page":"136","article-title":"Immunostaining of mesothelial cells: no reactivity with HLE\u2010I","volume":"33","author":"Guzman J","year":"1989","journal-title":"Acta Cytol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/91.1.18"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840070202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840070202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T21:15:45Z","timestamp":1698095745000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840070202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["10.1002\/dc.2840070202"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840070202","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}