{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:38:09Z","timestamp":1760981889179},"reference-count":6,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":5185,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1992,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>By coupling radiologic imaging procedures with a fine\u2010needle aspiration (FNA) technique, superficial and deep\u2010seated tumors of the thorax may be sampled for cytopathologic evaluation with relative ease, minimal trauma to the patient, and may avert unnecessary or contraindicated surgery. However, the cytodiagnostic limitations that apply to FNA specimens from other sites also obtain for tumors of the thoracic cavity. Although application of histo\u2010 and immunohistochemistry offers some expansion of cytodiagnostic limits, their inherent problems of technical failure and biological capriciousness demand a highly critical if not outright skeptical appraisal of the result when applied to cytology specimens. By extending the basic morphologic principles of cytodiagnosis to include fine structure, its limitations can be largely eliminated. Journals of pathology and specialized atlases contain detailed fine structural descriptions of essentially all recognized neoplasms, and the features that discriminate one neoplasm from another are now well recognized. In most instances, a few well\u2010preserved cells or cell groups obtained from an FNA can provide a morphological diagnosis that rivals or surpasses that of conventional paraffin sections of surgically biopsied material, when evaluated in concert with the cytology preparation. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840080319","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T02:08:29Z","timestamp":1172110109000},"page":"289-292","source":"Crossref","is-referenced-by-count":7,"title":["Rapid ultrastructural examination of FNAs in the diagnosis of intrathoracic tumors"],"prefix":"10.1002","volume":"8","author":[{"given":"Stanley M.","family":"Kurtz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"447","article-title":"A fast method for processing biological material for electron microscopy","volume":"23","author":"Bencosme SA","year":"1970","journal-title":"Lab Invest"},{"key":"e_1_2_1_3_2","volume-title":"Thin needle aspiration biopsy","author":"Frable WJ","year":"1983"},{"key":"e_1_2_1_4_2","volume-title":"Clinical ytopathology and spiration biopsy","author":"Ramzy I","year":"1990"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.17.1.19"},{"key":"e_1_2_1_6_2","first-page":"1637","article-title":"Advantages of a phosphate buffer for osmium tetroxide solutions in fixation","volume":"32","author":"Millionig G","year":"1961","journal-title":"J Appl Phys"},{"key":"e_1_2_1_7_2","first-page":"367","article-title":"Cytopathology and electron microscopy in the diagnosis of lung cancer by fine needle aspiration biopsies","volume":"22","author":"Bedrossian CWM","year":"1984","journal-title":"Patologia"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840080319","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840080319","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T12:56:05Z","timestamp":1698065765000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840080319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,5]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1992,5]]}},"alternative-id":["10.1002\/dc.2840080319"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840080319","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,5]]}}}