{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T22:40:20Z","timestamp":1695681620119},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":5001,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1992,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Helicobacter<\/jats:italic> ( formerly <jats:italic>Campylobacter) pylori<\/jats:italic> is frequently associated with chronic gastritis and peptic ulcer and has been implicated as an etiologic agent. Identification of <jats:italic>H. pylori<\/jats:italic> is important for specific treatment with antibiotics and bismuth compounds. We studied 27 patients who presented with symptoms of gastritis or peptic ulcer on whom paired gastric biopsies and gastric brushings for cytology had been performed. Biopsies were stained with H &amp; E and Warthin\u2010Starry or Giemsa for <jats:italic>H. pylori<\/jats:italic>. Previously, Papanicolaou\u2010stained brushings were restained with Giemsa and reviewed blindly by two cytologists. Cytologic examination revealed the characteristic 1\u20103 \u03bc curved or spiral gram\u2010negative bacilli embedded in mucus in 12 of 27 (44%) of cases. Biopsies showed <jats:italic>H. pylori<\/jats:italic> in 13 of 27 (48%) of cases. Cytology and histology were concordant in 22 of 27 (81%) of cases. Three cases were positive on biopsy, negative on cytology; two of these were unsatisfactory cytology specimens. Two cases were positive on cytology, negative on biopsy, apparently sampling artifacts. Papanicolaoustained slides were scored for several morphologic parameters; numbers of acute and chronic inflammatory cells and degree of cytologic atypia. None of these were predictive of the presence of <jats:italic>H. pylori<\/jats:italic>. We conclude that Giemsa\u2010stained gastric brushings are a useful complement to gastric biopsies in establishing the diagnosis of <jats:italic>H. pylori<\/jats:italic>. Diagn Cytopathol 1992;8:563\u2010566. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840080604","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T02:23:33Z","timestamp":1172111013000},"page":"563-566","source":"Crossref","is-referenced-by-count":3,"title":["<i>Helicobacter (campylobacter) pylori<\/i> in gastric brushing cytology"],"prefix":"10.1002","volume":"8","author":[{"given":"Pamela R.","family":"Edmonds","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael J.","family":"Carrozza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca M.","family":"Ruggiero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie A.","family":"Calafati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert C.","family":"Jann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/21548331.1987.11703288","article-title":"Peptic ulcer: an infectious disease?","volume":"22","author":"Marshall BJ","year":"1987","journal-title":"Hosp Pract"},{"key":"e_1_2_1_3_2","first-page":"45","article-title":"Helicobacter pylori and duodenal ulceration","volume":"26","author":"Lind CD","year":"1991","journal-title":"Hosp Pract"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.1998.00770.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)62541-5"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.264.21.2724"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1099\/00207713-39-4-397"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.150.5.951"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"436","DOI":"10.5694\/j.1326-5377.1985.tb113443.x","article-title":"Attempt to fulfill Koch's postulates of pyloric Campylobacter","volume":"142","author":"Marshall BJ","year":"1985","journal-title":"Med J Aust"},{"key":"e_1_2_1_10_2","first-page":"75","article-title":"Campylobacterassociated chronic gastritis","volume":"25","author":"Wyatt JI","year":"1990","journal-title":"Pathol Annu"},{"issue":"4","key":"e_1_2_1_11_2","first-page":"498","article-title":"Immunocytochemical identification of Helicobacter pylori in formalin\u2010fixed gastric biopsies","volume":"4","author":"Cartun RW","year":"1991","journal-title":"Modern Pathology"},{"key":"e_1_2_1_12_2","first-page":"205","article-title":"Identification of Campylobacter pylori in gastric biopsy smears","volume":"34","author":"Faverly D","year":"1990","journal-title":"Acta Cytologica"},{"key":"e_1_2_1_13_2","first-page":"211","article-title":"Cytologic diagnosis of Campylobacter pylori associated gastritis","volume":"34","author":"Davenport RD","year":"1990","journal-title":"Acta Cytologica"},{"key":"e_1_2_1_14_2","first-page":"204","article-title":"Cytodiagnosis of Campylobacter pylori in papanicolaou\u2010stained imprints of gastric biopsy specimens","volume":"35","author":"Pinto MM","year":"1991","journal-title":"Acta Cytologica"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840080604","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840080604","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T21:59:08Z","timestamp":1695679148000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840080604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,11]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1992,11]]}},"alternative-id":["10.1002\/dc.2840080604"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840080604","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,11]]}}}