{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:18:01Z","timestamp":1792304281067,"version":"4.4.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":4940,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Tubal metaplasia of the endocervix (TME), a condition that may be con\/used morphologically with glandular neoplasia, is frequently found in cone or hysterectomy specimens. To determine the frequency of detecting TME in cytologic smears, we retrospectively reviewed 28 Papanicolaou (Pap) smears from 22 women (mean age 39.1 yr; range 25\u201060 yr) with histologically proven TME. Our criteria for TME were the presence of two cell types in addition to endocervical secretory cells, i.e., peg cells (cells with dark and granular cytoplasm and elongate nuclei) and ciliated cells. All women had cervical cytology specimens obtained with an endocervical brush shortly before the procedures in which TME was diagnosed, and five also had at least one post\u2010procedure smear. Of 20 smears with an adequate, non\u2010neoplastic endocervical component, TME was found in 2 (10%). In these two, TME cells constituted 10% and &lt; 5% of all the glandular cells, respectively, and the percentage of ciliated cells in the TME was approximately 25% and 75%. In conclusion, TME was noted infrequently (10%) on the cervical cytosmears of women with histologically\u2010proven TME. This result corresponds to the histologic finding that TME typically involves the upper endocervix and glandular epithelium, with only 13% of the women having TME on the surface of the lower endocervix. Atypical glandular cells on cervical cytology are a problem for clinicians and pathologists alike. The differential diagnosis of such atypia, including TME, cells of the lower uterine segment, squamous intraepithelial lesion in glands and glandular neoplasia, is discussed.<\/jats:p>","DOI":"10.1002\/dc.2840090121","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T03:11:32Z","timestamp":1172113892000},"page":"98-105","source":"Crossref","is-referenced-by-count":44,"title":["Tubal metaplasia: A cytologic study with comparison to other neoplastic and non\u2010neoplastic conditions of the endocervix"],"prefix":"10.1002","volume":"9","author":[{"given":"Barbara S.","family":"Ducatman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen H.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon G.","family":"Jonasson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine L.","family":"Hogan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald A.","family":"Antonioli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gladwyn","family":"Leiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1967.tb03941.x"},{"key":"e_1_2_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198012000-00004"},{"key":"e_1_2_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199204000-00002"},{"key":"e_1_2_2_1_5_2","first-page":"1","article-title":"Tubal Metaplasia. A frequent potential pitfall in the cytologic diagnosis of endocervical glandular dysplasia on cervical smears","volume":"36","author":"Novotny DB","year":"1992","journal-title":"Acta Cytol"},{"key":"e_1_2_2_1_6_2","first-page":"325","article-title":"The cytologic diagnosis of adenocarcinoma in situ of the cervix uteri and related lesions. III. 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