{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T08:36:23Z","timestamp":1768638983724,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":4759,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1993,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fine\u2010needle aspiration biopsy (FNAB) has been recognized as a safe and reliable procedure in the evaluation of thyroid nodules. We herein report a case of a low\u2010grade mucoepidermoid carcinoma of the thyroid that was diagnosed with this technique. Examination of an intra\u2010operative FNAB showed cohesive clusters of polygonal squamoid cells with distinct cellular borders, uniform round nuclei, distinct nucleoli, and homogeneous amphophilic to cyanophilic cytoplasm. Focal keratin \u201cpearl\u201d formation was apparent, along with extracellular, lightly basophilic mucin deposits mantled by squamoid cells. These cytologic features are characteristic of low\u2010grade mucoepidermoid carcinoma, as seen in other anatomic sites. This impression was confirmed by examination of paraffin sections. Previous reports have indicated that mucoepidermoid thyroid carcinoma is an indolent, locally recurring lesion. However, in spite of low\u2010grade histology in our case, the neoplasm presented with distant metastases to bones, pleura, and lung.<\/jats:p>","DOI":"10.1002\/dc.2840090413","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T03:04:19Z","timestamp":1172113459000},"page":"438-443","source":"Crossref","is-referenced-by-count":21,"title":["Primary mucoepidermoid carcinoma of the thyroid: Diagnosis by fine\u2010needle aspiration biopsy"],"prefix":"10.1002","volume":"9","author":[{"given":"Richard S.","family":"Larson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark R.","family":"Wick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900501)65:9<2020::AID-CNCR2820650923>3.0.CO;2-#"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19840415)53:8<1741::AID-CNCR2820530821>3.0.CO;2-C"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197701)39:1<210::AID-CNCR2820390133>3.0.CO;2-H"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1984.tb02400.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830415)51:8<1505::AID-CNCR2820510825>3.0.CO;2-9"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199105000-00003"},{"key":"e_1_2_1_8_2","first-page":"1053","article-title":"Mucoepidermoid carcinoma of the bronchus","volume":"43","author":"Klacsmann PG","year":"1968","journal-title":"Cancer"},{"key":"e_1_2_1_9_2","first-page":"490","article-title":"Mucoepidermoid carcinoma: Review of 815 reported cases","volume":"28","author":"Eversole LR","year":"1970","journal-title":"J Oral Surg"},{"key":"e_1_2_1_10_2","first-page":"1053","article-title":"Mucoepidermoid carcinoma of the esophagus: Report of two cases","volume":"22","author":"Kay S","year":"1968","journal-title":"Endoscopy"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1985.tb02873.x"},{"key":"e_1_2_1_12_2","first-page":"145","article-title":"Mucoepidermoid carcinoma of the subglottis","volume":"101","author":"Tomita T","year":"1977","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_1_13_2","first-page":"1175","article-title":"Electron microscopic study of mucoepidermoid carcinoma in the pancreas","volume":"37","author":"Ohtsuki Y","year":"1987","journal-title":"Acta Pathol Jpn"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.46.1.65"},{"key":"e_1_2_1_15_2","first-page":"35","article-title":"Aspiration biopsy of salivary gland tumors: IV. 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