{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:18:42Z","timestamp":1791825522734,"version":"4.3.4"},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":4667,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1993,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Malakoplakia is an uncommon chronic granulomatous process that most commonly affects the urinary tract, but it may rarely recur in the female genital tract. It appears to result from a defect in macrophage function resulting in an inability to destroy ingested bacteria. We describe the fine needle aspiration cytology of malakoplakia in an 84\u2010yr\u2010old woman presenting with a large pelvic mass involving the apex of the vagina. The patient's history was significant for cervical squamous cell carcinoma in the remote past. CT\u2010guided needle aspiration yielded cellular smears with large numbers of isolated histiocytes, as well as polymorphonuclear leukocytes, lymphocytes, and plasma cells. The histiocytes had central nuclei and abundant granular cytoplasm containing target\u2010shaped, laminated bodies (Michaelis\u2010Gutmann bodies). These bodies were PAS positive and focally von Kossa positive. Large numbers of intracellular and extracellular bacteria were also seen on the smears. The characteristic cytologic findings obtained by needle aspiration were diagnostic of malakoplakia with a rare and unusual clinical presentation.<\/jats:p>","DOI":"10.1002\/dc.2840090518","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T03:01:03Z","timestamp":1172113263000},"page":"559-561","source":"Crossref","is-referenced-by-count":12,"title":["Malakoplakia of the vagina diagnosed by fine\u2010needle aspiration cytology"],"prefix":"10.1002","volume":"9","author":[{"given":"A. Joe","family":"Saad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa M.","family":"Donovan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luan D.","family":"Truong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197712292972601"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(74)80066-3"},{"key":"e_1_2_1_4_2","first-page":"457","article-title":"Role of fine needle aspiration biopsy in the diagnosis and management of malacoplakia","volume":"29","author":"Akhtar M","year":"1985","journal-title":"Acta Cytol"},{"key":"e_1_2_1_5_2","first-page":"48","article-title":"Cytologic diagnosis of prostatic malakoplakia. Report of three cases","volume":"31","author":"Cazzaniga MG","year":"1987","journal-title":"Acta Cytol"},{"key":"e_1_2_1_6_2","first-page":"53","article-title":"Diagnosis of intestinal malakoplakia by fine needle aspiration cytology","volume":"31","author":"Kumar PV","year":"1987","journal-title":"Acta Cytol"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(80)90134-9"},{"key":"e_1_2_1_8_2","first-page":"1342","article-title":"Malakoplakia of the vagina. First case report","volume":"47","author":"Van Der Watt JJ","year":"1973","journal-title":"S Afr Med J"},{"key":"e_1_2_1_9_2","first-page":"193","article-title":"Malakoplakia of the female genital tract","volume":"33","author":"Bose S","year":"1990","journal-title":"Indian J Pathol Microbiol"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840090518","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840090518","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T15:46:35Z","timestamp":1698248795000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840090518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,10]]},"references-count":8,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1993,10]]}},"alternative-id":["10.1002\/dc.2840090518"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840090518","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,10]]}}}