{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:47:50Z","timestamp":1759564070539},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":4546,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1994,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>One hundred and seven smears demonstrating a low\u2010grade squamous intraepithelial lesion (LSIL) were analyzed for features predicting subsequent biopsy confirmation. Twelve (29%) of 41 smears showing few LSIL cells were biopsy confirmed compared to 33 (60%) of 55 containing an intermediate number of LSIL cells and 9 (82%) of 11 displaying many LSIL cells (P &lt; 0.002). Thirty\u2010seven (47%) of 78 smears showing mainly condylomatous atypia (CA), 7 (54%) of 13 revealing predominantly cervical intraepithelial neoplasia 1 (CIN 1), and 10 (63%) of 16 displaying both CA and CIN 1 were histologically confirmed (N.S.). Biopsy confirmation was obtained in 35 (65%) of 54 women whose repeat smears obtained at colposcopy demonstrated SIL compared to four (15%) of 26 patients whose repeat smears were normal or contained atypical squamous cells of undetermined significance (P &lt; 0.001). These results suggest that the number of diagnostic cells in an LSIL smear predicts biopsy confirmation and affirm the validity of combining CA and CIN 1 under the category of LSIL in the Bethesda System. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840100103","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T02:38:32Z","timestamp":1172111912000},"page":"3-9","source":"Crossref","is-referenced-by-count":26,"title":["Low\u2010grade squamous intraepithelial lesions: Cytologic predictors of biopsy Confirmation"],"prefix":"10.1002","volume":"10","author":[{"given":"Scott","family":"Hall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. 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HPV testing: An objective measure of quality assurance in cervical cytopathology.Am J Clin Pathol(in press)."},{"key":"e_1_2_1_19_2","first-page":"778","article-title":"Routine colposcopic survey of patients with squamous atypia. A method for identifying cases with false\u2010negative smears","volume":"34","author":"Cecchini S","year":"1990","journal-title":"Acta Cytol"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(87)80004-2"},{"key":"e_1_2_1_21_2","first-page":"731","article-title":"Comparative utility of repeat Papanicolaou smears, cervicography, and colposcopy in the evaluation of atypical Papanicolaou smears","volume":"69","author":"Spitzer M","year":"1987","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_22_2","unstructured":"SedlisA.Histology\/cytology correlates using both Bethesda and traditional systems. 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