{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:56:11Z","timestamp":1773860171775,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":4546,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1994,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fine\u2010needle aspiration cytology (FNAC) of the testis was done in 31 children (33 aspirates) with acute lymphoblastic leukemia (ALL) either as part of an end\u2010therapy protocol (Group I, n = 20) or because of clinical suspicion of testicular relapse (Group II, n = 13). In Group I, none of the smears showed evidence of leukemic cells. However, two of these patients developed subsequent testicular relapse within 1 yr and were considered false\u2010negative cases. Blast cells were present in nine patients of Group II; in the remaining four patients no neoplastic cells were observed in the smears and none experienced a relapse after a mean follow\u2010up of 18 mo. Our findings indicate that FNAC can be a valuable method to evaluate clinically suspected testicular infiltration in children with ALL, and can be considered as an alternative procedure to surgical biopsy for screening testicular recurrence of childhood ALL. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840100112","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T02:38:32Z","timestamp":1172111912000},"page":"44-46","source":"Crossref","is-referenced-by-count":14,"title":["Fine\u2010needle aspiration cytology as a tool for the early detection of testicular relapse of acute lymphoblastic leukemia in children"],"prefix":"10.1002","volume":"10","author":[{"given":"Margarida Mendes","family":"de Almeida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rio","family":"Chagas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Valen \u00c7a","family":"de Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Evelina","family":"Mendon\u00e7a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196906)23:6<1290::AID-CNCR2820230608>3.0.CO;2-N"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197504)35:4<1203::AID-CNCR2820350426>3.0.CO;2-3"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810201)47:3<470::AID-CNCR2820470308>3.0.CO;2-T"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1542\/peds.43.6.1042","article-title":"Leukemia infiltration of the testes during bone marrow remission","volume":"43","author":"Finkelstein JZ","year":"1969","journal-title":"Pediatries"},{"key":"e_1_2_1_6_2","first-page":"212","article-title":"Testicular relapse in childhood leukemia","volume":"53","author":"Saiontz HI","year":"1978","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197612)38:6<2604::AID-CNCR2820380655>3.0.CO;2-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(80)80868-7"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1200\/JCO.1990.8.1.57","article-title":"The prognostic value of testicular biopsy in childhood acute lymphoblastic leukemia: A report from the Children's Cancer Study Group","volume":"8","author":"Miller DR","year":"1990","journal-title":"J Clin Oncol"},{"key":"e_1_2_1_10_2","doi-asserted-by":"crossref","unstructured":"NachmanJ PalmereNF SatherHN et al. 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