{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T12:55:29Z","timestamp":1753275329941},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,14]],"date-time":"2006-07-14T00:00:00Z","timestamp":1152835200000},"content-version":"vor","delay-in-days":4426,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1994,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To evaluate the efficacy of the Cytobrush method in aged patients, a comparative study between the Cytobrush smears and cotton swab smears from the uterine cervix was performed. Consecutive 319 cotton swab smears of the endocervix were attempted on aged patients (60\u201098 yr, average 77.5 yr) from 1987 to 1988 (A group). Subsequently 391 endocervical smears were attempted by the Cytobrush on aged patients (60\u2010100 yr, average 76.9 yr) from 1988 to 1990 (B group). The Cytobrush method was more effective in the following two points: (1) The rate of insert\u2010impossible case in B group (7.2%) was lower than A group (12.5%). (2) The rate of case containing endocervical columnar cells increased in B group (64.7%) compared with A group (47.7%). In contrast, benign epithelial fragments (BFs) were observed in 6.8% of A, in 28.4% of B group. In smears positive for squamous cancer, malignant epithelial fragments (MFs) were noted in 24.5% of A, and 55.1% of B group. Consequently, the differential diagnosis of MFs from BFs is of more importance on the Cytobrush smears of aged patients. \u00a9 1994 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840100404","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T03:58:43Z","timestamp":1172116723000},"page":"311-314","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy of the cytobrush method in aged patients"],"prefix":"10.1002","volume":"10","author":[{"given":"Noboru","family":"Koike","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Kasamatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"843","article-title":"Analysis of five sampling methods for the preparation of cervical smears","volume":"33","author":"Boon ME","year":"1989","journal-title":"Acta Cytol"},{"key":"e_1_2_1_3_2","first-page":"849","article-title":"Efficacy of the Cytobrush versus the cotton swab in the collection of endocervical cells","volume":"33","author":"Kristensen GB","year":"1989","journal-title":"Acta Cytol"},{"key":"e_1_2_1_4_2","first-page":"261","article-title":"The efficiency of the Cytobrush versus the cotton swab in the collection of endocervical cells in cervical smears","volume":"30","author":"Trimbos JB","year":"1986","journal-title":"Acta Cytol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840030317"},{"key":"e_1_2_1_6_2","first-page":"79","article-title":"Use of the Cytobrush for cervical sampling after cryotherapy","volume":"35","author":"Hoffman MS","year":"1991","journal-title":"Acta Cytol"},{"key":"e_1_2_1_7_2","first-page":"785","article-title":"Goblet\u2010like cells in atrophic vaginal smears and their histologic correlation","volume":"34","author":"Koike N","year":"1990","journal-title":"Acta Cytol"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(91)90623-Y"},{"key":"e_1_2_1_9_2","first-page":"57","article-title":"Exploiting the \u201ctooth\u2010pick effect\u201d of the Cytobrush by plastic embedding of cervical samples","volume":"35","author":"Boon ME","year":"1991","journal-title":"Acta Cytol"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fdc.2840100404","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.2840100404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T01:42:15Z","timestamp":1698111735000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.2840100404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,6]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1994,6]]}},"alternative-id":["10.1002\/dc.2840100404"],"URL":"https:\/\/doi.org\/10.1002\/dc.2840100404","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,6]]}}}