{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:38:09Z","timestamp":1760981889729},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,12]],"date-time":"2006-07-12T00:00:00Z","timestamp":1152662400000},"content-version":"vor","delay-in-days":4151,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[1995,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report three cases of well\u2010differentiated neuroendocrine carcinoma originating primarily in the anterior mediastinum which had been initially investigated by fine\u2010needle aspiration cytology in conjunction with immunocytochemistry and subsequently recognized as thymic in origin. Aspirates consisted of loosely cohesive or aggregated medium sized elements with round to oval nuclei and scanty cytoplasm. in all cases the Romanowsky stain provided an excellent delineation of definite paranuclear inclusion\u2010like structures having a semicircular or discoid appearance which appeared to contain cytokeratin by immunocytochemical studies and were very similar to the intermediate filament paranuclear \u201cbuttons\u201d found in neuroendocrine Merkel cell carcinoma of the skin. This appears to be a novel cytologic observation for thymic neuroendocrine carcinoma. We discuss the significance of the above cytologic and immunocytochemical findings and their possible role in the diagnosis of thymic neuroendocrine carcinoma by fine\u2010needle aspiration biopsy. \u00a9 1995 Wiley\u2010 Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840120216","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T03:34:11Z","timestamp":1172115251000},"page":"158-164","source":"Crossref","is-referenced-by-count":12,"title":["Neuroendocrine carcinoma of the thymus: Aspiration biopsy, immunocytochemistry, and clinicopathologic correlates"],"prefix":"10.1002","volume":"12","author":[{"given":"Giorgio","family":"Gherardi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Marveggio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Placidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0344-0338(88)80046-3"},{"key":"e_1_2_1_3_2","first-page":"35","article-title":"Neuroendocrine neoplasms of the mediastinum","volume":"8","author":"Wick MR","year":"1991","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_1_4_2","first-page":"201","article-title":"Carcinoid tumors and oat cell carcinomas of the thymus","volume":"11","author":"Rosai J","year":"1976","journal-title":"Pathol Annu"},{"key":"e_1_2_1_5_2","series-title":"2nd series","first-page":"171","volume-title":"Tumors of the thymus. 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