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The polygonal (or epithelial\u2010like) cell pattern may be seen with benign and malignant thymomas, germinomas, embryonal carcinoma, and many metastatic carcinomas. An intimate admixture of small lymphocytes with these epithelial cells may occur in this category. The small cell pattern may be produced by malignant non\u2010Hodgkin's lymphomas, neuroblastoma, carcinoid tumors, and metastatic oat cell carcinoma. Uncommon morphologic forms of thymoma and carcinoid tumors, as well as benign mesenchymal lesions, may yield a picture of a spindle\u2010cell proliferation. In addition to cytomorphology, the cytologist needs to integrate clinical, radio\u2010graphic, immunocytochemical, and ultrastructural data to formulate a final diagnosis. \u00a9 1995 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/dc.2840130512","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T05:13:24Z","timestamp":1172121204000},"page":"436-442","source":"Crossref","is-referenced-by-count":36,"title":["Differential diagnostic considerations and potential pitfalls in fine\u2010needle aspiration biopsies of the mediastinum"],"prefix":"10.1002","volume":"13","author":[{"given":"Kim R.","family":"Geisinger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.141.2.7291553"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830101)51:1<127::AID-CNCR2820510126>3.0.CO;2-Y"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1159\/000226008"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.180.1.1647039"},{"key":"e_1_2_1_6_2","first-page":"34","volume-title":"Tumors of the thymus","author":"Rosai J","year":"1976"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(78)80131-2"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00737071"},{"key":"e_1_2_1_9_2","first-page":"250","article-title":"Thymomas and thymic carcinomas","volume":"7","author":"Walker AN","year":"1990","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_1_10_2","first-page":"1","article-title":"Controversies regarding the pathology of thymomas","volume":"27","author":"Kornstein MJ","year":"1992","journal-title":"Pathol Annu"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(93)90014-8"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)60907-0"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19940515)73:10<2491::AID-CNCR2820731007>3.0.CO;2-6"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198207000-00007"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198210000-00003"},{"key":"e_1_2_1_16_2","first-page":"210","article-title":"Thymoma diagnosed by transthoracic fine needle aspiration","volume":"26","author":"Pak HY","year":"1982","journal-title":"Acta Cytol"},{"key":"e_1_2_1_17_2","first-page":"503","article-title":"Needle biopsy diagnosis of thymoma. 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