{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T09:05:28Z","timestamp":1767258328885,"version":"3.48.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T00:00:00Z","timestamp":1764201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Pancreatic medullary carcinoma is an extremely rare tumor classified as a histological subtype of pancreatic ductal adenocarcinoma. We report a case of a pancreatic medullary carcinoma and describe its cytological features. A 75\u2010year\u2010old woman presented with lower back pain, epigastric discomfort, and a tumor\u2010like lesion in the pancreatic body. Cytologic specimens obtained via endoscopic ultrasound\u2010guided fine\u2010needle aspiration revealed relatively uniform small round cells with a high nuclear\u2010to\u2010cytoplasmic ratio, appearing as isolated scattered cells or loosely aggregated small clusters in a bloody background containing mature lymphocytes. Histological examination showed cells similar to those observed in the cytological smear, and molecular testing revealed wild\u2010type\n                    <jats:italic>KRAS<\/jats:italic>\n                    and high microsatellite instability. Consequently, the patient was diagnosed with pancreatic medullary carcinoma. To our knowledge, only 33 cases of pancreatic medullary carcinoma have been reported to date, and this is the first report to describe its cytological features.\n                  <\/jats:p>","DOI":"10.1002\/dc.70056","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T05:43:49Z","timestamp":1764308629000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cytological Features of Pancreatic Medullary Carcinoma Diagnosed by Endoscopic Ultrasound\u2010Guided Fine Needle Aspiration"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-2307-9251","authenticated-orcid":false,"given":"Urara","family":"Okawa","sequence":"first","affiliation":[{"name":"Department of Diagnostic Pathology Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-2432-5421","authenticated-orcid":false,"given":"Keishi","family":"Mizuguchi","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyu","family":"Okuda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Ikeda","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Pathology Kanazawa University Hospital  Kanazawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,27]]},"reference":[{"key":"e_1_2_11_2_1","first-page":"328","volume-title":"Digestive System Tumours","author":"Gill A. 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Poor Differentiation, a Syncytial Growth Pattern, and Pushing Borders Suggest RER+","volume":"152","author":"Goggins M.","year":"1998","journal-title":"American Journal of Pathology"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(88)90571-5"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000050649"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-004-0037-y"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sipas.2024.100254"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2006.06.024"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-021-01178-0"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2014-102552"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65035-3"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v28.i40.5827"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24145"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22597"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70056","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T09:03:26Z","timestamp":1767258206000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.70056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,27]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/dc.70056"],"URL":"https:\/\/doi.org\/10.1002\/dc.70056","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"type":"print","value":"8755-1039"},{"type":"electronic","value":"1097-0339"}],"subject":[],"published":{"date-parts":[[2025,11,27]]},"assertion":[{"value":"2025-05-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}