{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:27:34Z","timestamp":1780324054398,"version":"3.54.1"},"reference-count":13,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2026,7]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n Diagnosis of adenoid cystic carcinoma (ACC) in salivary gland cytology specimens may be challenging due to overlapping features with cellular pleomorphic adenoma and monomorphic adenomas. Due to this difficulty, some are classified as salivary gland neoplasm of uncertain malignant potential. Criteria exist for the diagnosis of ACC but have not been statistically validated. This study analyzes the utility of published criteria for this purpose.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A series of 46 salivary gland tumors (26 ACC and 20 other basaloid neoplasms) were investigated by logistic regression analysis for the utility of 11 criteria used in the diagnosis of ACC.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The reproducibility of these criteria was fair to moderate (Cohen's kappa 0.2473\u20130.5482). Logistic regression showed that the presence of hyaline stroma and absence of plasmacytoid cells, myxoid stroma, or nuclear palisading supports the diagnosis of ACC.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The presence of hyaline stroma supports the diagnosis of ACC. While cell rings and \u201cfinger in glove\u201d structures were frequently seen in ACCs, they were not found to be useful according to the logistic regression analysis for the diagnosis of ACCs.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/dc.70116","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T04:16:41Z","timestamp":1774325801000},"page":"463-468","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cytomorphologic Predictors of Adenoid Cystic Carcinoma: Insights From a Multi\u2010Center Logistic Regression Study"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1344-6506","authenticated-orcid":false,"given":"Lester J.","family":"Layfield","sequence":"first","affiliation":[{"name":"Department of Pathology and Anatomical Sciences University of Missouri Columbia Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6564-3889","authenticated-orcid":false,"given":"Richard L.","family":"Cantley","sequence":"additional","affiliation":[{"name":"Department of Pathology Michigan Medicine Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Dodd","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of North Carolina Chapel Hill Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liron","family":"Pantanowitz","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Pittsburgh Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9342-3069","authenticated-orcid":false,"given":"Zubair","family":"Baloch","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Esebua","sequence":"additional","affiliation":[{"name":"Department of Pathology and Anatomical Sciences University of Missouri Columbia Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Maleki","sequence":"additional","affiliation":[{"name":"Department of Pathology Johns Hopkins Medical Institution Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Ge","sequence":"additional","affiliation":[{"name":"Biomedical Informatics, Biostatistics and Medical Epidemiology University of Missouri Columbia Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-26662-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.25482"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22604"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24962"},{"issue":"4","key":"e_1_2_8_6_1","first-page":"279","article-title":"Cytologic Diagnosis of Adenoid Cystic Carcinoma of Salivary Glands and Distinction From Basal Cell Adenoma","volume":"47","author":"Bai Y. P.","year":"2018","journal-title":"Zhonghua Bing Li Xue Za Zhi"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000326094"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/106.1.35"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000333988"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332543"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr\u20102014\u2010208114"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24573"},{"key":"e_1_2_8_13_1","first-page":"59","volume-title":"Monographs in Clinical Cytology","author":"Klijanienko J.","year":"2000"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.4103\/jomfp.jomfp_70_24"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70116","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.70116","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70116","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:50:44Z","timestamp":1780321844000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.70116"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,23]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/dc.70116"],"URL":"https:\/\/doi.org\/10.1002\/dc.70116","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,23]]},"assertion":[{"value":"2025-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}