{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:31:11Z","timestamp":1783020671728,"version":"3.54.6"},"reference-count":11,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    We report a case of a 57\u2010year\u2010old male with anaplastic transformation of papillary thyroid carcinoma (PTC) in metastatic lymph nodes. This case presents as a pitfall due to squamous differentiation in anaplastic thyroid carcinoma, which was initially misinterpreted as metastatic squamous cell carcinoma on fine needle aspiration (FNA) of the lymph node in the neck. Subsequent surgical resection reveals a unique rare occurrence of isolated anaplastic transformation of tall cell PTC in the metastatic lymph nodes, associated with the extremely rare co\u2010occurrence of\n                    <jats:italic>BRAF<\/jats:italic>\n                    p.V600E and\n                    <jats:italic>KRAS<\/jats:italic>\n                    p.G12R mutations.\n                  <\/jats:p>","DOI":"10.1002\/dc.70141","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T05:31:07Z","timestamp":1778045467000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Isolated Anaplastic Transformation of Tall Cell Papillary Thyroid Carcinoma in Metastatic Lymph Nodes With Extremely Rare Co\u2010Occurrence of\n                    <i>BRAF<\/i>\n                    p.\n                    <scp>V600E<\/scp>\n                    and\n                    <i>KRAS<\/i>\n                    p.\n                    <scp>G12R<\/scp>\n                    Mutations: A Unique Case"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3917-7318","authenticated-orcid":false,"given":"Alicia Ming Xi","family":"Chia","sequence":"first","affiliation":[{"name":"Department of Pathology Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9918-6930","authenticated-orcid":false,"given":"Lih Khuang","family":"Go","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9802-8754","authenticated-orcid":false,"given":"Hui Lin","family":"Teo","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6877-2347","authenticated-orcid":false,"given":"Jereme Yi Jin","family":"Gan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3333-1565","authenticated-orcid":false,"given":"Manish Mahadeorao","family":"Bundele","sequence":"additional","affiliation":[{"name":"Department of Pathology Tan Tock Seng Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine Tumours","author":"Erickson L. A.","year":"2025"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12022\u2010021\u201009665\u20102"},{"key":"e_1_2_7_4_1","volume-title":"WHO Classification of Tumours Editorial Board. Endocrine and Neuroendocrine Tumours","author":"Baloch Z. W.","year":"2025"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2020.0086"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078\u20100432.CCR\u201018\u20100373"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102265.2007.03077.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/acr\u201023\u201083"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI85271"},{"issue":"5","key":"e_1_2_7_10_1","first-page":"637","article-title":"Spindle Cell Squamous Carcinoma of the Thyroid: An Unusual Anaplastic Tumor Associated With Tall Cell Papillary Cancer","volume":"4","author":"Bronner M. P.","year":"1991","journal-title":"Modern Pathology"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0338"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097\u20100339(199912)21:6<413::aid\u2010dc10>3.0.co;2\u2010n"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70141","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.70141","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70141","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T18:09:22Z","timestamp":1783015762000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.70141"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,5]]},"references-count":11,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/dc.70141"],"URL":"https:\/\/doi.org\/10.1002\/dc.70141","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,5]]},"assertion":[{"value":"2026-02-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}