{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T03:55:30Z","timestamp":1790999730723,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Secretory carcinoma (SC) of the salivary gland, previously known as mammary analog SC, is a rare malignant neoplasm characterized by ETV6 gene rearrangements that most commonly arises in the parotid gland of middle\u2010aged to older adults. Several salivary gland neoplasms harbor a prominent lymphoid component, most classically Warthin tumor; however, SC is rarely associated with this feature. We present a case of a Warthin\u2010like secretory carcinoma with robust tumor\u2010associated lymphoid proliferation (TALP) in the parotid gland of a 69\u2010year\u2010old Caucasian male with a 30\u2010pack\u2010year smoking history. Fine needle aspiration (FNA) cytology demonstrated oncocytic\u2010appearing epithelial cells in a lymphocyte\u2010rich background with cystic debris, closely mimicking the cytomorphology of Warthin tumor. The subsequent parotidectomy revealed an epithelial neoplasm with mixed solid, cribriform, and cystic architecture, abundant eosinophilic luminal secretions, and robust TALP. Immunohistochemical studies on the resection specimen confirmed Warthin\u2010like secretory carcinoma. ETV6\u2010NTRK3 fluorescence in\u00a0situ hybridization was not performed, as the combined histomorphologic and immunohistochemical profile was considered diagnostic. This underrecognized variant poses a significant diagnostic pitfall, as overlapping morphologic features may lead to misclassification as Warthin tumor on cytology.<\/jats:p>","DOI":"10.1002\/dc.70189","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T10:25:32Z","timestamp":1785234332000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Warthin\u2010Like Secretory Carcinoma of the Parotid Gland: A Diagnostic Pitfall in Fine Needle Aspiration Cytology"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2673-6917","authenticated-orcid":false,"given":"Daniel","family":"Lauffenburger","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of North Carolina Hospitals  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laleh","family":"Hakima","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of North Carolina Hospitals  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181d9efcc"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002043"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-025-09990-w"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.31123"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.13845"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2015.64"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14772"},{"issue":"6","key":"e_1_2_9_9_1","first-page":"422","article-title":"Comparison of p63 and p40 (\u0394Np63) as Basal, Squamoid, and Myoepithelial Markers in Salivary Gland Tumors","volume":"24","author":"Owosho A. A.","year":"2016","journal-title":"Applied Immunohistochemistry & Molecular Morphology"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.23139"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22574"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000932"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2024.04.004"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.24175"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11207"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.13461"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncy.22288"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/dc.70120"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70189","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.70189","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70189","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T03:26:32Z","timestamp":1790997992000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.70189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,28]]},"references-count":17,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1002\/dc.70189"],"URL":"https:\/\/doi.org\/10.1002\/dc.70189","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,28]]},"assertion":[{"value":"2026-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}