{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T03:55:28Z","timestamp":1790999728385,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Thoracic lymph node enlargement is a common diagnostic finding and may be attributed to a broad spectrum of diseases, including granulomatous disorders, infections, and advanced malignancy. Although radiological modalities such as computed tomography (CT) and positron emission tomography\u2010computed tomography (PET\u2010CT) are widely employed for preliminary noninvasive assessment, their specificity in distinguishing benign from malignant cases remains restricted due to overlapping imaging appearance. Endobronchial ultrasound\u2010guided fine\u2010needle aspiration cytology (EBUS\u2010FNAC) has become an important minimally invasive diagnostic modality for mediastinal and hilar lymph nodes. This study aims to evaluate the diagnostic effectiveness of EBUS\u2010FNAC in thoracic lymphadenopathy and examine its correlation with CT and PET\u2010CT findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients whose EBUS FNAC samples were received in Cytology section of SKM pathology lab in a 1\u2010year period were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 174 patients were included. CT scan of all patients showed thoracic lymphadenopathy. Malignant pathology was identified in 45\/174 (25.8%) patients, granulomatous disease in 45\/174 (25.8%) patients, reactive lymphadenopathy in 83\/174 (47.7%) patients, and 1 patient's sample was concluded as inadequate (0.57%). Significant correlation was observed between lymph node size &gt;\u200915\u2009mm and disease involvement (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>EBUS\u2010FNAC is a safe diagnostic modality with high sensitivity and specificity for assessing thoracic lymph node enlargement. Integration of radiological features and cytological findings further strengthens diagnostic confidence. It should be adopted as a first\u2010line diagnostic technique before surgical intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dc.70190","type":"journal-article","created":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T06:47:22Z","timestamp":1785480442000},"page":"822-828","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Diagnostic Utility of Endobronchial Ultrasound\u2010Guided Fine\u2010Needle Aspiration Cytology (\n                    <scp>EBUS<\/scp>\n                    \u2010\n                    <scp>FNAC<\/scp>\n                    ) for Thoracic Lymphadenopathy: A Correlation Study With Radiological Findings"],"prefix":"10.1002","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0935-7116","authenticated-orcid":false,"given":"Nida","family":"Babar","sequence":"first","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2716-5027","authenticated-orcid":false,"given":"Asif","family":"Loya","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6629-8118","authenticated-orcid":false,"given":"Sajid","family":"Mushtaq","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6809-6884","authenticated-orcid":false,"given":"Maryam","family":"Hameed","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0128-5410","authenticated-orcid":false,"given":"Mudassar","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1826-8104","authenticated-orcid":false,"given":"Usman","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2022-8777","authenticated-orcid":false,"given":"Safana","family":"Sadaf","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9348-9762","authenticated-orcid":false,"given":"Sadaf","family":"Mufty","sequence":"additional","affiliation":[{"name":"Department of Pathology and Nuclear Medicine Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH&amp;RC)  Lahore Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"High\u2010Resolution CT of the Lung","author":"Webb W. 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