{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:59:32Z","timestamp":1790679572584,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Metastasis of renal cell carcinoma (RCC) to the head and neck region is rare, accounting for approximately 8%\u201314% of all RCC metastases. The thyroid gland is the most common site of metastasis in this region. However, RCC is known for its ability to metastasize to unusual anatomical sites, including the salivary glands. Approximately 0.1% of metastatic salivary gland neoplasms originate from renal malignancies, and the parotid gland is the most frequently involved site. Metastases to the submandibular and sublingual glands are considerably less common. In this report, we present a 62\u2010year\u2010old male patient who developed submandibular gland metastasis 18\u2009years after undergoing radical nephrectomy for clear cell renal cell carcinoma (CCRCC).<\/jats:p>","DOI":"10.1002\/dc.70212","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:28:36Z","timestamp":1790677716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Renal Clear Cell Carcinoma With Late Metastasis to the Submandibular Gland: A Case Report and Literature Review"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8609-7429","authenticated-orcid":false,"given":"Berfin Ekin","family":"Yildiz","sequence":"first","affiliation":[{"name":"Department of Pathology Haydarpasa Numune Training and Research Hospital, University of Health Sciences Turkey  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4020-9736","authenticated-orcid":false,"given":"Seda","family":"Mazmanoglu Atilman","sequence":"additional","affiliation":[{"name":"Department of Pathology Haydarpasa Numune Training and Research Hospital, University of Health Sciences Turkey  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7092-3391","authenticated-orcid":false,"given":"F\u00fcgen","family":"Aker","sequence":"additional","affiliation":[{"name":"Department of Pathology Haydarpasa Numune Training and Research Hospital, University of Health Sciences Turkey  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1148\/rg.336125110","article-title":"Metastatic Renal Cell Carcinoma: Radiologic Findings and Assessment of Response to Targeted Antiangiogenic Therapy by Using Multidetector CT","volume":"33","author":"Brufau B. 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B.","year":"2007","journal-title":"Head and Neck Pathology"},{"key":"e_1_2_9_6_1","first-page":"394","article-title":"Global Cancer Statistics 2018: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"68","author":"Bray F.","year":"2018","journal-title":"CA: A Cancer Journal for Clinicians"},{"key":"e_1_2_9_7_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/njms.njms_79_23","article-title":"Renal Cell Carcinoma Metastasizing to Salivary Glands: Systematic Review","volume":"15","author":"Gupta S.","year":"2024","journal-title":"National Journal of Maxillofacial Surgery"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S480747"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr362"},{"issue":"4","key":"e_1_2_9_10_1","first-page":"526","article-title":"A Case of Metastatic Renal Cell Carcinoma in Submandibular Gland","volume":"41","author":"Ham H. S.","year":"1998","journal-title":"Korean Journal of Otorhinolaryngology\u2010Head and Neck Surgery"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.35420\/jcohns.2021.32.3.296"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.5106\/jjshns.32.277"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.10.030"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.47176\/mjiri.34.175"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djaf060"}],"container-title":["Diagnostic Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70212","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/dc.70212","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/dc.70212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:28:38Z","timestamp":1790677718000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/dc.70212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":14,"alternative-id":["10.1002\/dc.70212"],"URL":"https:\/\/doi.org\/10.1002\/dc.70212","archive":["Portico"],"relation":{},"ISSN":["8755-1039","1097-0339"],"issn-type":[{"value":"8755-1039","type":"print"},{"value":"1097-0339","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]},"assertion":[{"value":"2026-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"dc.70212"}}