{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:00:48Z","timestamp":1790679648730,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Synovial sarcoma (SS) is a rare and aggressive soft tissue malignancy that is more common in the extremities and has an unusual occurrence in the head and neck region. SS has two main subtypes: biphasic and monophasic. Some rare subtypes include poorly differentiated (round cell), monophasic epithelial, calcifying\/ossifying, and myxoid types. Here, we present a rare case of a 61\u2010year\u2010old male with two left\u2010sided neck masses abutting the supraclavicular fossa. One of the masses was present for over a year and gradually increased in size. The second mass was noticed a week before he presented to our institution. The fine\u2010needle aspiration (FNA) specimen consists of tight clusters of monotonous epithelioid cells with scant amphophilic cytoplasm, hyperchromatic ovoid nuclei, increased mitotic activity (up to 6 per 10 HPF), and scattered apoptotic bodies. The tumor cells showed patchy expression for cytokeratins and claudin\u20104 and demonstrated strong and diffuse expression for TLE and SS18\u2010SSX, consistent with a diagnosis of synovial sarcoma. Deep morphological analysis and targeted immunohistochemical workup can aid in the diagnosis of this rare entity in the head and neck area.<\/jats:p>","DOI":"10.1002\/dc.70214","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:26:48Z","timestamp":1790677608000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Poorly Differentiated Synovial Sarcoma of the Superficial Neck: Diagnostic Approach in a Fine\u2010Needle Aspiration Specimen"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6087-2335","authenticated-orcid":false,"given":"Rachelle P.","family":"Mendoza","sequence":"first","affiliation":[{"name":"Department of Pathology and Cell Biology Columbia University Irving Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5340-5544","authenticated-orcid":false,"given":"Olivia A.","family":"Sagan","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Rochester Medical Center  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0008-8826","authenticated-orcid":false,"given":"Madhurya","family":"Ramineni","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Rochester Medical Center  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9061-2017","authenticated-orcid":false,"given":"Dakila M.","family":"Gabutan","sequence":"additional","affiliation":[{"name":"School of Professional Studies Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1700-0961","authenticated-orcid":false,"given":"Sharlin","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Rochester Medical Center  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23252"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2024.102627"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/2036361318776495"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/2054270418760437"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/184891"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159\u20108290.CD\u201014\u20101246"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12736"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2019.05.001"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(15)00583\u20105"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xocr.2021.100342"},{"issue":"11","key":"e_1_2_9_12_1","first-page":"2272","article-title":"The SYT\u2010SSX Fusion Protein and Histological Epithelial Differentiation in Synovial Sarcoma: Relationship With Extracellular Matrix Remodeling","volume":"6","author":"Saito T.","year":"2013","journal-title":"International Journal of Clinical and Experimental Pathology"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2014.09.002"},{"issue":"5","key":"e_1_2_9_14_1","first-page":"456","article-title":"Myxoid Synovial Sarcoma: An Underappreciated Morphologic Subset","volume":"12","author":"Krane J. 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