{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:04:06Z","timestamp":1790687046349,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Rapid on\u2010site evaluation (ROSE) improves specimen adequacy in thyroid fine\u2010needle aspiration biopsy (FNAB), but the conventional cytopathologist\u2010attended model may be difficult to sustain in high\u2010volume centers. Cytologist\u2010performed ROSE has been proposed as a practical alternative. This study aimed to evaluate the impact of cytologist\u2010performed ROSE on specimen adequacy, diagnostic category distribution, number of needle passes, number of prepared slides, and repeat cytology rates in thyroid FNAB.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively compared thyroid FNAB cases performed during two sequential periods at a single institution: a pre\u2010ROSE period, during which FNAB was performed without on\u2010site cytological assessment, and a post\u2010ROSE period, during which ROSE was performed by a cytologist who had completed a structured three\u2010month training program under the supervision of a pathologist. Specimen adequacy, Bethesda System diagnostic categories, number of needle passes, number of prepared slides, and repeat cytology rates were compared between the two periods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 916 patients were included, comprising 262 cases in the pre\u2010ROSE period and 654 cases in the post\u2010ROSE period. Specimen adequacy increased significantly from 49.2% in the pre\u2010ROSE period to 85.8% in the post\u2010ROSE period (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Bethesda category I diagnoses decreased from 50.4% to 14.8%, whereas Bethesda category II diagnoses increased from 39.7% to 73.5% after ROSE implementation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The mean number of needle passes decreased from 3.27\u2009\u00b1\u20090.49 to 2.12\u2009\u00b1\u20090.92, and the mean number of prepared slides decreased from 11.86\u2009\u00b1\u20095.39 to 7.21\u2009\u00b1\u20093.13 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 for both). The repeat cytology rate also decreased from 8.8% to 5.2% (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.043).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Cytologist\u2010performed ROSE was associated with significantly improved specimen adequacy, a marked reduction in nondiagnostic thyroid aspirates, fewer needle passes and prepared slides, and a lower repeat cytology rate. These findings suggest that a structured cytologist\u2010performed ROSE model may be a feasible and effective approach for improving specimen adequacy in thyroid FNAB, particularly in high\u2010volume centers with limited cytopathology resources.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/dc.70215","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:48:07Z","timestamp":1790686087000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Cytologist\u2010Performed Rapid on\u2010Site Evaluation on Adequacy and Diagnostic Performance in Thyroid Fine Needle Aspiration Cytology"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-0238","authenticated-orcid":false,"given":"T\u00fclay","family":"Ko\u00e7","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Pathology Sivas Cumhuriyet University  Sivas T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9936-6710","authenticated-orcid":false,"given":"Canan","family":"Karabulut","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pathology Sivas Cumhuriyet University  Sivas T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4059-9946","authenticated-orcid":false,"given":"\u015eeyhmus","family":"Kaya","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pathology Sivas Cumhuriyet University  Sivas T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5156-6923","authenticated-orcid":false,"given":"\u0130smail","family":"\u015ealk","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Radiology Sivas Cumhuriyet University  Sivas T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7150-8835","authenticated-orcid":false,"given":"Ersin","family":"Tuncer","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Pathology Sivas Cumhuriyet University  Sivas 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