{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T10:39:47Z","timestamp":1792492787742,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Diagnostic Cytopathology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Striated duct adenoma (SDA) is a rare benign salivary gland neoplasm with limited cytologic characterization. We report a case of SDA with cytologic, histologic, immunohistochemical, and molecular correlation to further define its morphologic spectrum and diagnostic considerations. The patient was a 62\u2010year\u2010old male with a submandibular gland mass. Cytologically, the specimen demonstrated loose clusters of monomorphic epithelial cells ranging from cuboidal to rare elongated or slightly spindled morphology, with moderate amounts of variable oncocytic cytoplasm. Nuclei were ovoid and normochromatic with occasional nuclear grooves and infrequent pseudoinclusions. No significant nuclear atypia, mitotic activity, necrosis, or stromal components were identified. Using the 2nd Edition Milan System Classification, the case was categorized as Neoplasm: Benign (Category IVA). Histologic examination confirmed SDA, and next\u2010generation sequencing identified an\n                    <jats:italic>IDH2<\/jats:italic>\n                    p.R172M mutation. The cytologic and histologic features of SDA overlap with other salivary gland neoplasms, especially those with oncocytic\/oncocytoid features. Definitive classification relies on histopathologic correlation and, when available, supportive molecular evidence of an\n                    <jats:italic>IDH2<\/jats:italic>\n                    mutation.\n                  <\/jats:p>","DOI":"10.1002\/dc.70222","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:57:33Z","timestamp":1792490253000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>FNA<\/scp>\n                    of Striated Duct Adenoma: Cytologic, Histologic, and Molecular Features of a Rare Salivary Gland Neoplasm"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-3211-2420","authenticated-orcid":false,"given":"Chayanan","family":"Puriwat","sequence":"first","affiliation":[{"name":"Department of Pathology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"},{"name":"Department of Pathology, Faculty of Medicine Siriraj Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1502-9848","authenticated-orcid":false,"given":"Rong","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Golrokh","family":"Sepehr","sequence":"additional","affiliation":[{"name":"Department of Pathology Atrius Health Part of Optum  Needham Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1036-6367","authenticated-orcid":false,"given":"Peter M.","family":"Sadow","sequence":"additional","affiliation":[{"name":"Department of Pathology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6588-6549","authenticated-orcid":false,"given":"Jeremy","family":"Richmon","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery Massachusetts Eye and Ear and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9043-7171","authenticated-orcid":false,"given":"William C.","family":"Faquin","sequence":"additional","affiliation":[{"name":"Department of Pathology Massachusetts General Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Head and Neck Tumours","author":"WHO Classification of Tumours Editorial 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