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With only a few innovative formulations in development, it is necessary to identify pharmacophores and novel strategies for creating new drugs. The conjugation of dissimilar pharmacophoric moieties to design hybrid molecules with an attractive therapeutic profile is an emerging paradigm in the contemporary drug development regime. The recent decade witnessed the remarkable biological potential of 1,3,5\u2010triazine framework in the development of various chemotherapeutics. The appending of the 1,3,5\u2010triazine nucleus to biologically relevant moieties has delivered exciting results. 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