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Pyochelin (Pch) is a catecholate type of phenolate siderophore produced and utilized by the pathogen\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    to assimilate iron when colonizing the vertebrate host. Zingerone, is active component present in ginger, a dietary herb known for its anti\u2010virulent approach against\n                    <jats:italic>P. aeruginosa<\/jats:italic>\n                    . In the present study, zingerone was exploited to act as a good substitute for existing antibiotics, known to have developed resistance by most pathogens. Encouraging results were obtained by docking analysis of pyochelin\u2010zingerone conjugate with FptA, the outer membrane receptor of pyochelin. Conjugate also showed anti\u2010quorum sensing activity and also inhibited swimming, swarming, and twitching motilities as well as biofilm formation\n                    <jats:italic>in vitro<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/ddr.21781","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T23:12:46Z","timestamp":1609801966000},"page":"605-615","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Design, synthesis, molecular docking, anti\u2010quorum sensing, and anti\u2010biofilm activity of pyochelin\u2010zingerone conjugate"],"prefix":"10.1002","volume":"82","author":[{"given":"Anu","family":"Nosran","sequence":"first","affiliation":[{"name":"Department of Microbiology Panjab University  Chandigarh 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