{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T21:09:16Z","timestamp":1771708156593,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Phlegmonous duodenitis is an extremely rare condition, and only a few cases have been previously reported. Here, we report a case of phlegmonous duodenitis caused by <jats:italic>Streptococcus parasanguinis<\/jats:italic> and <jats:italic>Escherichia coli<\/jats:italic> in a 78\u2010year\u2010old immunocompromised patient with diabetes mellitus and immunosuppressive drugs. Abdominal computed tomography showed diffuse thickening of the duodenum and gastric antrum, and esophagogastroduodenoscopy revealed some erosions with purulent discharge and reddish and edematous mucosa in the duodenal bulb. A bacteriological culture test detected the two abovementioned bacteria and established the diagnosis of phlegmonous duodenitis. Following the initiation of antibiotic treatment, his condition rapidly improved. Endoscopists should be aware of this rare entity and pay attention to the endoscopic duodenal findings similar to those of phlegmonous gastritis, particularly in immunocompromised patients who develop abdominal symptoms with severe inflammation.<\/jats:p>","DOI":"10.1002\/deo2.212","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T08:15:34Z","timestamp":1675325734000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Phlegmonous duodenitis in an immunocompromised patient"],"prefix":"10.1002","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3871-9478","authenticated-orcid":false,"given":"Daisuke","family":"Miyagishima","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Numazu City Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoto","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Numazu City Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromasa","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Numazu City Hospital  Shizuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.53.2741"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.54.4257"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.5230\/jgc.2016.16.3.195"},{"key":"e_1_2_5_5_1","article-title":"Successful antimicrobial treatment of phlegmonous gastritis: A case report and literature review","volume":"2018","author":"Iqbal M","year":"2018","journal-title":"Case Rep Hematol"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.0707-17"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-021-02999-9"},{"key":"e_1_2_5_8_1","first-page":"1197","article-title":"Phlegmonous gastritis and streptococcal toxic shock syndrome: An almost lethal combination","volume":"25","author":"Elisabeth P","year":"2021","journal-title":"Indian J Crit Med"},{"key":"e_1_2_5_9_1","first-page":"1322","article-title":"Phlegmonous duodenitis complicating multiple myeloma: A successfully treated case","volume":"82","author":"Kneafsey PD","year":"1987","journal-title":"Am J Gastroenterol"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0025802418794577"}],"container-title":["DEN Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/deo2.212","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/deo2.212","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/deo2.212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T07:44:01Z","timestamp":1747295041000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/deo2.212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,2]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/deo2.212"],"URL":"https:\/\/doi.org\/10.1002\/deo2.212","archive":["Portico"],"relation":{},"ISSN":["2692-4609","2692-4609"],"issn-type":[{"value":"2692-4609","type":"print"},{"value":"2692-4609","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,2]]},"assertion":[{"value":"2022-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e212"}}