{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:32:49Z","timestamp":1755225169558,"version":"3.43.0"},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T00:00:00Z","timestamp":1713657600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An 83\u2010year\u2010old male underwent three transgastric punctures with endoscopic ultrasound\u2010guided fine\u2010needle aspiration for the examination of a pancreatic body tumor. After a diagnosis of resectable pancreatic cancer and undergoing distal pancreatectomy, the patient was administered postoperative adjuvant chemotherapy with oral S\u20101 for 6 months, and carcinoembryonic antigen and carbohydrate antigen 19\u20109 levels were bimonthly evaluated. Carbohydrate antigen 19\u20109 levels continually increased to 4638.1 U\/mL at 45 months post\u2010fine\u2010needle aspiration. Endoscopic ultrasound\u2010guided showed a 25 mm low\u2010echoic, irregularly shaped, and heterogeneous tumor with clear margins protruding from the mucosa outside the gastric wall, and biopsy confirmed adenocarcinoma. Since the immunostaining findings of the specimen matched those of the previously resected specimen, needle tract seeding (NTS) due to puncture of the pancreatic cancer was identified as the cause. After a pylorus\u2010preserving gastrectomy at 46 months post\u2010fine\u2010needle aspiration, postoperative chemotherapy initiation, comprising gemcitabine and nab\u2010paclitaxel, was initiated; however, the patient died despite these interventions as he developed multiple peritoneal dissemination. Although rare, the incidence of NTS will increase in the future owing to the expected extended survival in post\u2010pancreatic cancer resection cases. We suggest regular upper gastrointestinal endoscopy and endoscopic ultrasound\u2010guided evaluations for patients who are at risk for NTS can facilitate early detection. Furthermore, it is extremely relevant to share experiences of encountered NTS cases in practice and extend knowledge of its varying endoscopic appearances.<\/jats:p>","DOI":"10.1002\/deo2.368","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T01:19:55Z","timestamp":1713748795000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A case of needle tract seeding with endoscopic findings of progression over time"],"prefix":"10.1002","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8158-9544","authenticated-orcid":false,"given":"Go","family":"Sawai","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1272-5175","authenticated-orcid":false,"given":"Katsuyuki","family":"Dainaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshida","family":"Juichiro","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Inada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akifumi","family":"Fukui","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Nishimura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoya","family":"Tomatsuri","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Okuyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Society Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,21]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep22978"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.13912"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-018-1506-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyy190"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.14120"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdv295"},{"key":"e_1_2_6_8_1","first-page":"2113","article-title":"Needle tract seeding after endoscopic ultrasound\u2010guided tissue acquisition of pancreatic tumors: A nationwide survey in Japan","volume":"12","author":"Kitano M","year":"2022","journal-title":"Dig Endosc"}],"container-title":["DEN 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