{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T21:41:25Z","timestamp":1755034885173,"version":"3.41.2"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T00:00:00Z","timestamp":1718064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Despite endometriosis being a relatively\u00a0common chronic gynecological condition\u00a0in women of childbearing age, small bowel endometriosis is rare. Presentations can vary from completely asymptomatic to reported symptoms of abdominal pain, bloating, and diarrhea. The following two cases depict very atypical manifestations of ileal endometriosis that presented as obscure intermittent gastrointestinal bleeding and bowel obstruction\u00a0requiring surgical intervention. The first case describes a previously healthy\u00a040\u2010year\u2010old\u00a0woman with severe symptomatic iron\u00a0deficiency anemia and intermittent melena. A small bowel\u00a0enteroscopy\u00a0diagnosed multiple ulcerated strictures in the distal small bowel as the likely culprit.\u00a0Despite nonsteroidal anti\u2010inflammatory drug\u2010induced enteropathy being\u00a0initially\u00a0considered as the likely etiology,\u00a0histopathological examination of the resected distal ileal segment revealed evidence of endometriosis.\u00a0The second case describes a 66\u2010year\u2010old with a presumptive diagnosis of Crohn's disease who reported a\u00a010\u2010year\u00a0history of intermittent perimenstrual abdominal pain, diarrhea, and nausea with vomiting. Following two subsequent episodes of acute bowel obstruction and surgical resection of the patient's stricturing terminal ileal disease, histopathological examination demonstrated active chronic inflammation\u00a0with\u00a0endometriosis. Small bowel endometriosis should be considered as an unusual differential diagnosis in women who may\u00a0present with\u00a0obscure gastrointestinal bleeding from the small bowel or recurrent bowel obstruction.<\/jats:p>","DOI":"10.1002\/deo2.395","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T05:14:23Z","timestamp":1718169263000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rare\u00a0presentations of small bowel endometriosis"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9559-2411","authenticated-orcid":false,"given":"Anthony","family":"Sakiris","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Gold Coast University Hospital Gold Coast Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0162-2883","authenticated-orcid":false,"given":"Ezaam Naik","family":"Fraz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Gold Coast University Hospital Gold Coast Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arvinf","family":"Rajandran","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Gold Coast University Hospital Gold Coast Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Allen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sooraj","family":"Pillai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep Kakkadasam","family":"Ramaswamy","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Gold Coast University Hospital Gold Coast Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sneha","family":"John","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Gold Coast University Hospital Gold Coast Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2018.06.001"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i42.15616"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2016.06.023"},{"key":"e_1_2_6_5_1","article-title":"Endometriosis of the small bowel: A diagnostic enigma","volume":"13","author":"Mehmood S","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-2029-z"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg513"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq057"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.55.5.391"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/742035"}],"container-title":["DEN Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/deo2.395","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T12:45:45Z","timestamp":1746189945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/deo2.395"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,11]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1002\/deo2.395"],"URL":"https:\/\/doi.org\/10.1002\/deo2.395","archive":["Portico"],"relation":{},"ISSN":["2692-4609","2692-4609"],"issn-type":[{"type":"print","value":"2692-4609"},{"type":"electronic","value":"2692-4609"}],"subject":[],"published":{"date-parts":[[2024,6,11]]},"assertion":[{"value":"2024-04-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e395"}}