{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:11:17Z","timestamp":1790172677233,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25K19293"],"award-info":[{"award-number":["25K19293"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Metastasis of lung cancer to the small intestine is rare and often diagnosed only after life\u2010threatening complications such as perforation or obstruction. We report a case of small intestinal metastasis from pulmonary large cell carcinoma, diagnosed using balloon\u2010assisted endoscopy (BAE) performed for obscure gastrointestinal bleeding (OGIB). A 73\u2010year\u2010old male patient previously underwent right upper lung lobectomy for stage IA1 large cell carcinoma. At 4\u00a0months postoperatively, he presented with melena and anemia. Upper and lower endoscopy and computed tomography failed to identify the bleeding source, prompting capsule endoscopy (CE), which revealed a jejunal ulcer. Subsequent BAE revealed an ulcerative lesion with submucosal tumor\u2010like elevated margins. Histopathological examination of the biopsy specimen showed proliferation of atypical cells with large nuclei, morphologically consistent with the previously diagnosed lung carcinoma. Considering the patient's good performance status and the presence of a solitary lesion, laparoscopic small bowel resection was performed. Histopathological findings of the resected small bowel specimen were consistent with the primary pulmonary lesion. The patient received postoperative chemotherapy and has remained recurrence\u2010free for 1\u00a0year. This case underscores the significance of CE and BAE in evaluating OGIB, particularly in patients with a history of lung cancer. Early endoscopic diagnosis may facilitate timely surgical intervention and enhance patient outcomes.<\/jats:p>","DOI":"10.1002\/deo2.70244","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T15:02:21Z","timestamp":1763132541000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Small Intestinal Metastasis From Pulmonary Large Cell Carcinoma Detected by Capsule Endoscopy and Balloon\u2010assisted Endoscopy, Followed by Early Surgical Resection: A Case Report"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0908-0135","authenticated-orcid":false,"given":"Yoshihiro","family":"Yokota","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science Shiga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3505-7835","authenticated-orcid":false,"given":"Masashi","family":"Ohno","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science Shiga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science Shiga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Nishida","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shiga University of Medical Science Shiga Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Shiratori","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery Shiga University of Medical Science Shiga 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