{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T14:10:16Z","timestamp":1790604616263,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The risk of post\u2010endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) needs to be predicted in order to take adequate preventive measures in individual cases. The aim of this study was to develop a clinical prediction rule for PEP in biliary ERCP for patients with intact papilla.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a multicenter prospective cohort study to investigate the adverse events of biliary ERCP in patients with intact papilla. A total of 3739 patients were prospectively enrolled at 36 hospitals in western Japan between April 2017 and March 2018. Data on patient\u2010related factors, operator\u2010related factors, procedure\u2010related factors, and preventative measures were collected. A multivariable logistic regression was used to identify predictors for PEP, and a scoring model was developed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The scoring model included 11 factors: age younger than 50 years (2 points), female sex (1 point), ASA 3 (\u20102 points), cholangitis (\u20101 point), hypoamylasemia (\u20101 point), obstruction of the main pancreatic duct at the pancreatic head (\u20102 points), cannulation time &gt;20\u00a0min (1 point), guidewire insertion into the pancreatic duct (3 points), intraductal ultrasonography (1 point), biopsy (1 point), and total procedure time &gt;60\u00a0min (2 points). The area under the receiver operating characteristic curve of this model was 0.729. All cases were stratified into three groups according to the total score: low\u2010risk, intermediate\u2010risk, and high\u2010risk groups, with an incidence of PEP of 1.6%, 6.0%, and 17.7%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This scoring model stratified the risk of PEP in individual ERCP cases with intact papilla fairly well.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/deo2.70245","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T06:02:39Z","timestamp":1763445759000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Clinical Scoring Model to Predict Post\u2010Endoscopic Retrograde Cholangiopancreatography Pancreatitis in Biliary Endoscopic Retrograde Cholangiopancreatography for Patients With Intact Papilla: A Large Multicenter Prospective Cohort Study"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0768-1801","authenticated-orcid":false,"given":"Koichi","family":"Fujita","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Yodogawa Christian Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujiro","family":"Yazumi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Medical Research Institute Kitano Hospital PIIF Tazuke Kofukai  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisakazu","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Japanese Red Cross Wakayama Medical Center  Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Asada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Japanese Red Cross Osaka Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Nebiki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Osaka City General Hospital  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Hanada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology JA Onomichi General Hospital Hiroshima Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuya","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Multidisciplinary Internal Medicine Tottori University Faculty of Medicine Tottori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2844-7838","authenticated-orcid":false,"given":"Toru","family":"Maruo","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Fukuoka University Chikushi Hospital Fukuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7308-4311","authenticated-orcid":false,"given":"Mamoru","family":"Takenaka","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Kindai University Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Kamada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Neurology Faculty of Medicine Kagawa University Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chishio","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Shin Beppu Hospital  Oita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidefumi","family":"Nishikiori","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Oita San\u2010ai Medical Center  Oita 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