{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T14:59:07Z","timestamp":1790175547303,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:00:00Z","timestamp":1771027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:00:00Z","timestamp":1771027200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      The Kyoto Classification of Gastritis enables endoscopic assessment of\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      (\n                      <jats:italic>H. pylori<\/jats:italic>\n                      ) infection status and gastric cancer risk. Initially developed for image\u2010enhanced endoscopy, texture and color enhancement imaging (TXI) allows us to easily distinguish differences in mucosal structure and color. The aim of this study was to evaluate the use of TXI in the visibility of endoscopic findings of gastritis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective analysis using prospectively collected endoscopic data from a prospective, single\u2010center study, in which 220 patients undergoing esophagogastroduodenoscopy were enrolled. Endoscopic images were obtained using both white light imaging (WLI) and TXI (TXI\u20101 and TXI\u20102). Ten endoscopists (five experts and five trainees) independently evaluated 52 matched image sets, scoring visibility on a 5\u2010point scale. Inter\u2010rater reliability was assessed using intraclass correlation coefficients. Objective color analysis using the CIE L*a*b* color space and \u0394E* values was also performed for map\u2010like redness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>TXI\u20101 improved visibility for diffuse redness, spotty redness, map\u2010like redness, patchy redness, atrophic border, red streak, and the regular arrangement of collecting venules. Visibility of intestinal metaplasia was also enhanced by TXI\u20101, although to a lesser extent than other findings. TXI\u20101 demonstrated \u201cmoderate\u201d to \u201csubstantial\u201d inter\u2010rater reliability. Objective colorimetric analysis confirmed significantly greater \u0394E* values with TXI\u20101 versus WLI for map\u2010like redness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      TXI\u20101 enhances the visibility of key endoscopic features of\n                      <jats:italic>H. pylori<\/jats:italic>\n                      \u2013associated gastritis. TXI\u20101 may serve as a useful tool for endoscopic assessment of\n                      <jats:italic>H. pylori<\/jats:italic>\n                      \u2013associated gastritis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>The study protocol was registered in the University Hospital Medical Information Network Clinical Trials Registry (UMIN000045323).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/deo2.70297","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T16:21:17Z","timestamp":1771086077000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Texture and Color Enhancement Imaging for the Kyoto Classification of Gastritis: Evaluation of Visibility and Color 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