{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:07:29Z","timestamp":1784228849094,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2027,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Amyloidosis, characterized by the deposition of abnormal protein fibrils in organs, is classified as systemic or localized. Amyloid light chain (AL)\u2010type localized amyloidosis is uncommon, particularly when confined to the gastrointestinal tract. Herein, we report a case of localized gastrointestinal AL\u2010type amyloidosis that was incidentally detected and remained endoscopically and clinically stable over a 5\u2010year follow\u2010up period.<\/jats:p>\n                  <jats:p>The patient, a man in his 40s, had undergone a colonoscopy for colorectal cancer screening, during which scattered erosions were detected in the colon. Amyloid deposits were identified on biopsy. No cardiac or renal involvement, or evidence of multiple myeloma, was found. He was ultimately diagnosed with localized AL\u2010type gastrointestinal amyloidosis. Following diagnosis, the patient underwent regular surveillance with transoral and transanal small\u2010bowel endoscopy. No endoscopic progression or gastrointestinal symptoms were observed during the follow\u2010up period, and the patient remained asymptomatic. This case suggests that conservative observation may be reasonable in carefully selected patients after exclusion of systemic involvement.<\/jats:p>","DOI":"10.1002\/deo2.70343","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T06:15:39Z","timestamp":1778134539000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Localized Gastrointestinal Light Chain (AL) Amyloidosis Under Surveillance for Five Years: A Case Report"],"prefix":"10.1002","volume":"7","author":[{"given":"Shunsuke","family":"Kojimahara","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Dokkyo Medical University School of Medicine  Tochigi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Tominaga","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Dokkyo Medical University School of Medicine  Tochigi 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