{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:08:37Z","timestamp":1784228917914,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2027,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Necator americanus<\/jats:italic>\n                    infection is now rare in developed countries but remains an important cause of iron\u2010deficiency anemia and abdominal symptoms in individuals with relevant epidemiological backgrounds. A 59\u2010year\u2010old Filipino man with long\u2010standing unexplained iron\u2010deficiency anemia was admitted to our hospital for epigastric pain associated with choledocholithiasis. Although biliary enzymes improved after endoscopic treatment, his abdominal pain persisted. Subsequent gastrointestinal investigations, including upper gastrointestinal endoscopy, colonoscopy, and small\u2010bowel capsule endoscopy, revealed multiple parasites distributed throughout the gastrointestinal tract. Image\u2010enhanced endoscopy using narrow\u2010band imaging clearly improved visualization of the parasites compared with conventional white\u2010light imaging, facilitating their identification and endoscopic removal. Genetic analysis of the extracted worms confirmed\n                    <jats:italic>N. americanus<\/jats:italic>\n                    infection. The patient was treated with pyrantel pamoate, which resulted in the resolution of abdominal symptoms and improvement of iron\u2010deficiency anemia. Follow\u2010up stool examination confirmed eradication of the parasite. This case highlights the importance of considering hookworm infection in patients with persistent iron\u2010deficiency anemia and abdominal pain, even in developed countries. In addition, image\u2010enhanced endoscopy and capsule endoscopy are valuable diagnostic tools for detecting hookworms and assessing their distribution within the gastrointestinal tract.\n                  <\/jats:p>","DOI":"10.1002\/deo2.70352","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T08:02:38Z","timestamp":1779436958000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Endoscopic Diagnosis of\n                    <i>Necator americanus<\/i>\n                    Infection Presenting With Persistent Iron\u2010Deficiency Anemia: Usefulness of Image\u2010Enhanced Endoscopy and Capsule Endoscopy"],"prefix":"10.1002","volume":"7","author":[{"given":"Tomohiro","family":"Takebe","sequence":"first","affiliation":[{"name":"First Department of Medicine Hamamatsu University School of Medicine Shizuoka Japan"},{"name":"Department of Gastroenterology Yaizu City Hospital Shizuoka 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Hamamatsu University School of Medicine Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra032492"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S443625"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12664-015-0611-2"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-7393"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2017.55.4.417"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68653-4"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1021467"},{"issue":"5","key":"e_1_2_10_9_1","first-page":"626","article-title":"Image of the Month: Hookworm Infection Observed via a Narrow\u2010band Imaging System","volume":"109","year":"2014","journal-title":"American 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