{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T11:07:19Z","timestamp":1783940839070,"version":"3.55.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2027,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Scintigraphy\u2010negative Meckel's diverticulum (MD) is diagnostically challenging in children, particularly when the underlying pathology differs between cases. Technetium\u201099\n                    <jats:sup>m<\/jats:sup>\n                    pertechnetate scintigraphy is widely used for diagnosis; however, false\u2010negative results may occur when ectopic gastric mucosa is absent or when the diverticulum is inverted. We report two pediatric cases with contrasting scintigraphy\u2010negative MD in which intestinal ultrasound (IUS) suggested target lesions, and double balloon enteroscopy (DBE) enabled direct diagnosis and preoperative localization.\n                  <\/jats:p>\n                  <jats:p>Case 1 was a 13\u2010year\u2010old boy with recurrent abdominal pain and hematochezia. IUS revealed localized ileal wall thickening with a hyperechoic polypoid lesion, and transanal DBE identified a pedunculated ulcerated mass approximately 80\u00a0cm proximal to the ileocecal valve. Surgical pathology confirmed inverted MD with ectopic gastric mucosa. Case 2 was an 11\u2010year\u2010old girl with recurrent abdominal pain initially treated as ileitis. IUS revealed localized ileal wall thickening with increased vascularity and a blind\u2010ending tubular structure, and DBE showed a double\u2010lumen appearance consisting of the true ileal lumen and a blind\u2010ending diverticular lumen. Pathology confirmed MD without ectopic mucosa. DBE enabled direct diagnosis and preoperative marking without complications in both cases. These cases suggest that IUS may help identify target lesions and that DBE is useful for definitive diagnosis and preoperative localization in children with suspected MD despite negative scintigraphy.<\/jats:p>","DOI":"10.1002\/deo2.70379","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T10:41:21Z","timestamp":1783939281000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Two Contrasting Scintigraphy\u2010Negative Pediatric Meckel's Diverticula Identified and Localized by Intestinal Ultrasound and Double\u2010Balloon Enteroscopy: A Report of Two Cases"],"prefix":"10.1002","volume":"7","author":[{"given":"Saki","family":"Kasai","sequence":"first","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masumi","family":"Nagata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Jimbo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyasu","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichiro","family":"Miyake","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Juntendo University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuyoshi","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo Japan"},{"name":"Department of Pediatrics and Neonatology Juntendo University Shizuoka Hospital  Shizuoka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Kudo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Go","family":"Miyano","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Juntendo University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromichi","family":"Shoji","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Juntendo University Faculty of Medicine  Tokyo 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