{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:24:26Z","timestamp":1788449066800,"version":"build-2803163510"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:00:00Z","timestamp":1788393600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["DEN Open"],"published-print":{"date-parts":[[2027,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Angiosarcoma is a rare, aggressive vascular malignancy, and gastrointestinal involvement is uncommon. We report disseminated angiosarcoma with multifocal small\u2010bowel involvement presenting as suspected small\u2010bowel bleeding, in which small\u2010bowel capsule endoscopy (SBCE) and double\u2010balloon endoscopy (DBE) were diagnostically useful. A man in his 60s presented with recurrent melena and transfusion\u2010dependent anemia. SBCE showed active jejunal bleeding with multiple ulcerative lesions, and antegrade DBE revealed hemorrhagic tumors with luminal narrowing. Retrograde DBE demonstrated additional ileal and colonic lesions. Computed tomography showed small\u2010bowel stenosis, mesenteric dissemination, bone metastases, and soft\u2010tissue infiltration around an abdominal aortic stent graft. The patient died 7 weeks after transfer. Autopsy confirmed disseminated angiosarcoma involving the small intestine and mesentery, with the greatest tumor burden around the aortic graft, suggesting a possible periaortic origin. This case highlights the complementary roles of SBCE and DBE and provides rare clinicopathological correlation with autopsy findings.<\/jats:p>","DOI":"10.1002\/deo2.70408","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T15:00:24Z","timestamp":1788447624000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Disseminated Angiosarcoma With Multifocal Small\u2010Bowel Involvement Presenting as Suspected Small\u2010Bowel Bleeding"],"prefix":"10.1002","volume":"7","author":[{"given":"Mayu","family":"Tomita","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Tashiro","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiharu","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazunori","family":"Adachi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahide","family":"Ebi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naotaka","family":"Ogasawara","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akana","family":"Hinokimoto","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology Aichi Medical University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyonori","family":"Tsuzuki","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology Aichi Medical University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanao","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Aichi Medical University School of Medicine  Nagakute Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(10)70023\u20101"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478\u2010200403000\u201000002"},{"key":"e_1_2_10_4_1","first-page":"702","article-title":"Angiosarcoma Related to Vascular Prostheses: A Systematic Review","volume":"40","author":"Moulakakis K. G.","year":"2010","journal-title":"European Journal of Vascular and Endovascular Surgery"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v29.i3.561"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000485345"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i19.4565"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000346398"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvscit.2025.102095"},{"key":"e_1_2_10_10_1","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000037932","article-title":"Pathogenesis, and Management of Angiosarcoma Associated With Implants and Foreign Body: Clinical Cases and Research Updates","volume":"103","author":"Etiology S. 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