{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:49:07Z","timestamp":1792100947275,"version":"4.4.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2001,4,17]],"date-time":"2001-04-17T00:00:00Z","timestamp":987465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Psychobiology"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>It has been reported in the rat that postnatal manipulations can induce robust and persistent effects on offspring neurobiology and behavior, mediated in part via effects on maternal care. There have, however, been few studies of the effects of postnatal manipulations on maternal care. Here, we describe and compare the effects on maternal behavior on postnatal days 1\u201312 of two manipulations, early handling (EH, 15\u2010min isolation per day) and early deprivation (ED, 4\u2010hr isolation per day), relative to our normal postnatal husbandry procedure. Maternal behavior was measured at five time points across the dark phase of the reversed L:D cycle. EH yielded an increase in arched\u2010back nursing across several time points but did not affect any other behavior. ED stimulated a bout of maternal behavior such that licking and arched\u2010back nursing were increased at the time of dam\u2013litter reunion, although not at any other time point. Neither EH nor ED affected weaning weight significantly. Importantly, within\u2010treatment variation was high relative to these between\u2010treatment effects. \u00a9 2001 John Wiley &amp; Sons, Inc. Dev Psychobiol 38: 239\u2013251, 2001<\/jats:p>","DOI":"10.1002\/dev.1018","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T21:24:42Z","timestamp":1030310682000},"page":"239-251","source":"Crossref","is-referenced-by-count":219,"title":["Comparison of the effects of early handling and early deprivation on maternal care in the rat"],"prefix":"10.1002","volume":"38","author":[{"given":"Christopher R.","family":"Pryce","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Bettschen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joram","family":"Feldon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,4,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/dev.420060406"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/dev.420040209"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.9.5335"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00110-4"},{"key":"e_1_2_1_6_1","first-page":"269","volume-title":"Society, stress and disease: Childhood and adolescence","author":"Denenberg V. 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