{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:41:36Z","timestamp":1786977696243,"version":"build-2736575974"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,4,4]],"date-time":"2008-04-04T00:00:00Z","timestamp":1207267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Developmental Psychobiology"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Juvenile female rats show maternal\u2010like behavior toward pups. The purpose of the following experiment was to investigate whether the HPA axis, through the use of early separation manipulations that alter HPA functioning in rats, plays a role in the juvenile response to foster pups. Female rats were early deprived or maternally separated for 5 hours daily from PND 2 to 14 and compared to animal facility\u2010reared rats. Deprivation or separation increased CRH\u2010R1 IR in the juvenile PVN, but had no other effects on other HPA measures or on maternal behavior. Pup\u2010exposure during the juvenile period blunted corticosterone levels after acute and repeated pup\u2010exposures when compared to exposure to novelty and conspecifics respectively. Repeated exposures to pups also increased CRH\u2010R1 IR relative to isolation during the juvenile period. Overall, the data suggest that although pup\u2010exposure affects corticosterone levels, the HPA axis does not relate to juvenile maternal behavior in the present experiments. \u00a9 2008 Wiley Periodicals, Inc. 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